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Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

Author
CLOZEL, M; BREU, V; RAMUZ, H; BURRI, K; CASSAL, J.-M; FISCHLI, W; GRAY, G. A; HIRTH, G; LÖFFLER, B.-M; MÜLLER, M; NEIDHART, W
F. Hoffman-La Roche Ltd, preclin. res., pharma div., 4002 Basel, Switzerland
Source

Nature (London). 1993, Vol 365, Num 6448, pp 759-761 ; ref : 31 ref

CODEN
NATUAS
ISSN
0028-0836
Scientific domain
Multidisciplinary
Publisher
Nature Publishing, London
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Animal Antagoniste Chimiothérapie Contraction musculaire Endothéline 1 In vitro In vivo Muscle lisse Physiopathologie Protéine G Protéine liaison Récepteur biologique Traitement Vaisseau sanguin Vasoconstriction Vasodilatation RO 462005 Appareil circulatoire pathologie
Keyword (en)
Animal Antagonist Chemotherapy Muscle contraction Endothelin 1 In vitro In vivo Smooth muscle Pathophysiology G protein Binding protein Biological receptor Treatment Blood vessel Vasoconstriction Vasodilation Cardiovascular disease
Keyword (es)
Animal Antagonista Quimioterapia Contracción muscular Endothelina 1 In vitro In vivo Músculo liso Fisiopatología Proteína G Proteína enlace Receptor biológico Tratamiento Vaso sanguíneo Vasoconstricción Vasodilatación Aparato circulatorio patología
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F04 Vasodilator agents. Cerebral vasodilators

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3747575

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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