Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist
- Author
- CLOZEL, M; BREU, V; RAMUZ, H; BURRI, K; CASSAL, J.-M; FISCHLI, W; GRAY, G. A; HIRTH, G; LÖFFLER, B.-M; MÜLLER, M; NEIDHART, W
F. Hoffman-La Roche Ltd, preclin. res., pharma div., 4002 Basel, Switzerland - Source
Nature (London). 1993, Vol 365, Num 6448, pp 759-761 ; ref : 31 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antagoniste Chimiothérapie Contraction musculaire Endothéline 1 In vitro In vivo Muscle lisse Physiopathologie Protéine G Protéine liaison Récepteur biologique Traitement Vaisseau sanguin Vasoconstriction Vasodilatation RO 462005 Appareil circulatoire pathologie
- Keyword (en)
- Animal Antagonist Chemotherapy Muscle contraction Endothelin 1 In vitro In vivo Smooth muscle Pathophysiology G protein Binding protein Biological receptor Treatment Blood vessel Vasoconstriction Vasodilation Cardiovascular disease
- Keyword (es)
- Animal Antagonista Quimioterapia Contracción muscular Endothelina 1 In vitro In vivo Músculo liso Fisiopatología Proteína G Proteína enlace Receptor biológico Tratamiento Vaso sanguíneo Vasoconstricción Vasodilatación Aparato circulatorio patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F04 Vasodilator agents. Cerebral vasodilators
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3747575
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/365759a0 
https://dx.doi.org/10.1038/365759a0
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