Structure-activity relationships of C-terminal endothelin hexapeptide antagonists
- Author
- DOHERTY, A. M1 ; CODY, W. L1 ; HALEEN, S. J; LADOUCEUR, D. M; HILL, K. E; FLYNN, M. A; REYNOLDS, E. E; DEPUE, P. L1 ; HE, J. X1 ; WAITE, L. A1 ; LEONARD, D. M1 ; LEITZ, N. L1 ; DUDLEY, D. T; RAPUNDALO, S. T; HINGORANI, G. P
[1] Warner-Lambert Co., Parke-Davis Pharmaceutical Research, dep. medicinal chemistry, Ann Arbor MI 48105, United States - Source
Journal of medicinal chemistry (Print). 1993, Vol 36, Num 18, pp 2585-2594 ; ref : 58 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aminoacide C terminal Animal Antagoniste Appareil circulatoire Encéphale Endothéline Fixation biologique Hexapeptide In vitro Lapin Rat Relation structure activité Récepteur peptidergique Système nerveux central Vaisseau sanguin Ventricule cardiaque Récepteur endothéline Lagomorpha Mammalia Rodentia Vertebrata
- Keyword (en)
- C terminal aminoacid Animal Antagonist Circulatory system Brain (vertebrata) Endothelin Biological fixation Hexapeptide In vitro Rabbit Rat Structure activity relation Peptidergic receptor Central nervous system Blood vessel Heart ventricle Lagomorpha Mammalia Rodentia Vertebrata
- Keyword (es)
- Aminoácido C terminal Animal Antagonista Aparato circulatorio Encéfalo Endothelina Fijación biológica Hexapéptido In vitro Conejo Rata Relación estructura actividad Receptor peptidérgico Sistema nervioso central Vaso sanguíneo Ventrículo cardíaco Lagomorpha Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F09 Miscellaneous
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3754553
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00070a001 
https://dx.doi.org/10.1021/jm00070a001
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