Peptidomimetic inhibitors of renin incorporating topographically modified isosteres spanning the P1(→P3)-P1' sites
- Author
- PLUMMER, M; HAMBY, J. M; HINGORANI, G; BATLEY, B. L; RAPUNDALO, S. T
Warner-Lambert Co., Parke-Davis pharmaceutical res., dep. chemistry, Ann Arbor MI 48106, United States - Source
Bioorganic & medicinal chemistry letters (Print). 1993, Vol 3, Num 10 ; 1911, 2119-2124
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antihypertenseur Dipeptide Fixation biologique Inhibiteur enzyme Relation structure activité Renin Structure moléculaire Ethylène(dihydroxy) Isostère Aspartic endopeptidases Enzyme Hydrolases Proteinases
- Keyword (en)
- Biological activity Antihypertensive agent Dipeptides Biological fixation Enzyme inhibitor Structure activity relation Renin Molecular structure Aspartic endopeptidases Enzyme Hydrolases Proteinases
- Keyword (es)
- Actividad biológica Antihipertensivo Dipéptido Fijación biológica Inhibidor enzima Relación estructura actividad Renin Estructura molecular Aspartic endopeptidases Enzima Hydrolases Proteinases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F05 Antihypertensive agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3773820
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0960-894X(01)81029-5 
https://dx.doi.org/10.1016/S0960-894X(01)81029-5
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