Synthesis and CLOGP correlation of imidooxy anticonvulsants
- Author
- FARRAR, V. A1 ; CIECHANOWICZ-RUTKOWSKA, M; ANDREWS, C. W; CORY, M; NICHOLSON, J. M; SCOTT, K. R1 ; GROCHOWSKI, J; SERDA, P; PILATI, T; FILIPPINI, G; HINKO, C. N; AFIF EL-ASSADI; MOORE, J. A1 ; EDAFIOGHO, I. O1
[1] Howard univ., coll. pharmacy pharmacal sci., dep. medicinal chemistry, Washington DC 20059, United States - Source
Journal of medicinal chemistry (Print). 1993, Vol 36, Num 23, pp 3517-3525 ; ref : 38 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Analyse rayons X Animal Anticonvulsivant Cristallographie In vivo Lipophilie Modèle moléculaire Modélisation Propriété physicochimique Propriété physique Rat Relation structure activité Spirane 2-Azaspiro[4.4]nonane-1,3-dione(2-benzyloxy) Pyrrolidine dérivé Pyrrolidine-2,4-dione dérivé Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity X ray analysis Animal Anticonvulsant Crystallography In vivo Lipophily Molecular model Modeling Physicochemical properties Physical properties Rat Structure activity relation Spiran Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Análisis rayos X Animal Anticonvulsivante Cristalografía In vivo Lipofilia Modelo molecular Modelización Propiedad fisicoquímica Propiedad física Rata Relación estructura actividad Espirano Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B06 Anticonvulsants. Antiepileptics. Antiparkinson agents
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3835195
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00075a005 
https://dx.doi.org/10.1021/jm00075a005
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