Synthesis of novel modified dipeptide inhibitors of human collagenase : β-mercapto carboxylic acid derivatives
- Author
- BESZANT, B; BIRD, J; GASTER, L. M; HARPER, G. P; HUGHES, I; KARRAN, E. H; MARKWELL, R. E; MILES-WILLIAMS, A. J; SMITH, S. A
SmithKline Beecham Pharmaceuticals, discovery res., Harlow Essex CM19 5AD, United Kingdom - Source
Journal of medicinal chemistry (Print). 1993, Vol 36, Num 25, pp 4030-4039 ; ref : 28 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Aminoamide Composé benzénique Diastéréoisomère Ester In vitro In vivo Inhibiteur enzyme Interstitial collagenase Thiol Phénylalanine(4-méthoxy-N-[2-(1-mercapto-2-méthoxycarbonyléthyl)-4-méthylvaléryl]) méthylamide Enzyme Hydrolases Metalloendopeptidases Proteinases
- Keyword (en)
- Biological activity Aminoamide Benzenic compound Diastereomer Ester In vitro In vivo Enzyme inhibitor Interstitial collagenase Thiol Enzyme Hydrolases Metalloendopeptidases Proteinases
- Keyword (es)
- Actividad biológica Aminoamida Compuesto bencénico Diasteréomero Ester In vitro In vivo Inhibidor enzima Interstitial collagenase Tiol Enzima Hydrolases Metalloendopeptidases Proteinases
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C02 Aliphatic compounds
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3871341
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00077a006 
https://dx.doi.org/10.1021/jm00077a006
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