Synthesis and biological evaluation of N4-substituted imidazo- and v-triazolo[4,5-d]pyridazine nucleosides
- Author
- BUSSOLARI, J. C1 ; KAKARLA RAMESH1 ; STOECKLER, J. D; SHIH-FONG CHEN; PANZICA, R. P1
[1] Univ. Rhode Island, dep. medicinal chemistry, Kingston RI 02881, United States - Source
Journal of medicinal chemistry (Print). 1993, Vol 36, Num 25, pp 4113-4120 ; ref : 45 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Adenosine deaminase Anticancéreux Inhibiteur enzyme Nucléoside 1,2,3-Triazolo[4,5-d]pyridazine(4-amino-1-[β-D-ribofuranosyl]) Imidazo[4,5-d]pyridazin-4-one(4,5-dihydro-1-[β-D-ribofuranosyl]) Imidazo[4,5-d]pyridazine(4-amino-1-[β-D-ribofuranosyl]) Enzyme Hydrolases
- Keyword (en)
- Biological activity Adenosine deaminase Antineoplastic agent Enzyme inhibitor Nucleoside Enzyme Hydrolases
- Keyword (es)
- Actividad biológica Adenosine deaminase Anticanceroso Inhibidor enzima Nucleósido Enzima Hydrolases
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C07 Carbohydrates. Nucleosides and nucleotides / 001C03C07B Nucleosides, nucleotides and oligonucleotides
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3879712
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00077a017 
https://dx.doi.org/10.1021/jm00077a017
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