Studies on antiulcer drugs. VII: 2-Guanidino-4-pyridylthiazoles as histamine H2-receptor antagonists with potent gastroprotective effects against nonsteroidal antiinflammatory drug-induced injury
- Author
- KATSURA, Y; INOUE, Y; TOMISHI, T; ISHIKAWA, H; TAKASUGI, H
Fujisawa Pharmaceutical Co., Ltd, New Drug Research Laboratories, Yodogawa-ku, Osaka 532, Japan - Source
Journal of medicinal chemistry (Print). 1994, Vol 37, Num 1, pp 57-66 ; ref : 25 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antagoniste Antiulcéreux Carboxamide Chien Cycle 5 chaînons Cycle 6 chaînons Guanidines Hétérocycle azote Hétérocycle soufre azote In vivo Pyridine dérivé Rat Récepteur histaminergique H2 Thiazole dérivé Pyridine6-acétamidométhyl-2-[2-(2-[diaminométhylèneamino]thiazol-4-yl]) Carnivora Fissipedia Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Antagonist Antiulcer agent Carboxamide Dog Five membered ring Six membered ring Guanidines Nitrogen heterocycle Sulfur nitrogen heterocycle In vivo Pyridine derivatives Rat H2 receptor Thiazole derivatives Carnivora Fissipedia Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Antagonista Antiulceroso Carboxamida Perro Ciclo 5 eslabones Ciclo 6 eslabones Guanidinas Heterociclo nitrógeno Heterociclo azufre nitrógeno In vivo Piridina derivado Rata Receptor histaminérgico H2 Tiazol derivado Carnivora Fissipedia Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06D Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3895462
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00027a007 
https://dx.doi.org/10.1021/jm00027a007
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