Open back door in a molecular dynamics simulation of acetylcholinesterase
- Author
- GILSON, M. K1 ; STRAATSMA, T. P1 ; MCCAMMON, J. A1 ; RIPOLL, D. R; FAERMAN, C. H; AXELSEN, P. H; SILMAN, I; SUSSMAN, J. L
[1] Univ. Houston, dep. chemistry, Houston TX 77204-5641, United States - Source
Science (Washington, D.C.). 1994, Vol 263, Num 5151, pp 1276-1278
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Accessibilité moléculaire Acetylcholinesterase Activité enzymatique Acétylcholine Mécanisme Méthode dynamique moléculaire Relation structure activité Simulation Site actif Substrat Carboxylic ester hydrolases Enzyme Esterases Hydrolases
- Keyword (en)
- Molecular accessibility Acetylcholinesterase Enzymatic activity Acetylcholine Mechanism Molecular dynamics method Structure activity relation Simulation Active site Substrate Carboxylic ester hydrolases Enzyme Esterases Hydrolases
- Keyword (es)
- Accesibilidad molecular Acetylcholinesterase Actividad enzimática Acetilcolina Mecanismo Método dinámico molecular Relación estructura actividad Simulación Lugar activo Substrato Carboxylic ester hydrolases Enzima Esterases Hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E04 Hydrolases
- Discipline
- Analytical, structural and metabolic biochemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3963879
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.8122110 
https://dx.doi.org/10.1126/science.8122110
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