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On the mechanism of enzymatic inactivation of bleomycin. The β-aminoalaninamide moiety as an enzyme-dependent molecular switch

Author
SUGIYAMA, T1 ; OHNO, M1 ; SHIBASAKI, M1 ; OTSUKA, M; SUGIURA, Y; KOBAYASHI, S; MAEDA, K
[1] Univ. Tokyo, fac. pharmaceutical sci., Bunkyo-ku, Tokyo 113, Japan
Source

Bioorganic & medicinal chemistry letters (Print). 1994, Vol 4, Num 5, pp 705-710

ISSN
0960-894X
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Animal Antibiotique Anticancéreux Bléomycine Enzyme Foie In vitro Inactivation métabolique Métabolisme Souris Mammalia Rodentia Vertebrata
Keyword (en)
Animal Antibiotic Antineoplastic agent Enzyme Liver In vitro Metabolic inactivation Metabolism Mouse Mammalia Rodentia Vertebrata
Keyword (es)
Animal Antibiótico Anticanceroso Enzima Hígado In vitro Inactivación metabólica Metabolismo Ratón Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
3967550

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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