On the mechanism of enzymatic inactivation of bleomycin. The β-aminoalaninamide moiety as an enzyme-dependent molecular switch
- Author
- SUGIYAMA, T1 ; OHNO, M1 ; SHIBASAKI, M1 ; OTSUKA, M; SUGIURA, Y; KOBAYASHI, S; MAEDA, K
[1] Univ. Tokyo, fac. pharmaceutical sci., Bunkyo-ku, Tokyo 113, Japan - Source
Bioorganic & medicinal chemistry letters (Print). 1994, Vol 4, Num 5, pp 705-710
- ISSN
- 0960-894X
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antibiotique Anticancéreux Bléomycine Enzyme Foie In vitro Inactivation métabolique Métabolisme Souris Mammalia Rodentia Vertebrata
- Keyword (en)
- Animal Antibiotic Antineoplastic agent Enzyme Liver In vitro Metabolic inactivation Metabolism Mouse Mammalia Rodentia Vertebrata
- Keyword (es)
- Animal Antibiótico Anticanceroso Enzima Hígado In vitro Inactivación metabólica Metabolismo Ratón Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3967550
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0960-894X(01)80184-0 
https://dx.doi.org/10.1016/S0960-894X(01)80184-0
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