Influence of the chromatographic capacity factor (log K') as an index of lipophilicity in the antibacterial activity of a series of 6-fluoroquinolones : relationship between physico-chemical and structural properties and their hydrophobicity
- Author
- MARTORELL, C1 ; CALPENA, A. C; ESCRIBANO, E; POBLET, J. M; FREIXAS, J1
[1] ITEVE, SA Laboratories, res. dep., 43202 Tarragona, Spain - Conference name
- Spanish group of chromatography and related techniques. Scientific meeting (21 ; Granada 1992-10-21)
- Source
Journal of chromatography. 1993, Vol 655, Num 2, pp 177-184 ; ref : 18 ref
- CODEN
- JOCRAM
- ISSN
- 0021-9673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Conference Paper
- Language
- English
- Keyword (fr)
- Activité biologique Antibactérien Chromatographie HPLC Chromatographie phase inverse Etude expérimentale Facteur capacité Fluor Composé organique Lipophilie Modèle mathématique Paire ion Quinolone dérivé
- Keyword (en)
- Biological activity Antibacterial agent HPLC chromatography Reversed phase chromatography Experimental study Capacity factor Fluorine Organic compounds Lipophily Mathematical model Ion pair Quinolone derivative
- Keyword (es)
- Actividad biológica Antibacteriano Cromatografía HPLC Cromatografìa fase inversa Estudio experimental Factor capacidad Fluor Compuesto orgánico Lipofilia Modelo matemático Par ión Quinolone derivado
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C04 Analytical chemistry / 001C04B Chromatographic methods and physical methods associated with chromatography / 001C04B02 Other chromatographic methods
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- Analytical chemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3996765
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/0021-9673(93)83221-D 
https://dx.doi.org/10.1016/0021-9673(93)83221-D
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