Optically active antifungal azoles. III: Synthesis and antifungal activity of sulfide and sulfonamide derivatives of (2R,3R)-2-(2,4-difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-butanol
- Author
- TASAKA, A; TERANISHI, K; MATSUSHITA, Y; TAMURA, N; HAYASHI, R; OKONOGI, K; ITOH, K
Takeda Chemical Industries Ltd, pharmaceutical res. div., pharmaceutical res. lab. III, Yodogawa-ku, Osaka 532, Japan - Source
Chemical and pharmaceutical bulletin. 1994, Vol 42, Num 1, pp 85-94
- CODEN
- CPBTAL
- ISSN
- 0009-2363
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Maruzen, Tokyo
- Publication country
- Japan
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antifongique Candida albicans Composé benzénique Configuration absolue Cycle 5 chaînons Fluor Composé organique Hydroxysulfure organique Hétérocycle azote In vitro In vivo Souris Sulfonamide Triazole dérivé 1,2,4-Triazole-2-propanesulfonique acide(β-[2,4-difluorophényl]-β-hydroxy-α-méthyl) dialkylamide Butan-2-ol(2-[2,4-difluorophényl]-3-hétérylthio-1-[1,2,4-triazol-2-yl]) Butan-2-ol(2-[2,4-difluorophényl]-3-mercapto-1-[1,2,4-triazol-2-yl]) Fungi Imperfecti Fungi Mammalia Rodentia Thallophyta Vertebrata
- Keyword (en)
- Biological activity Antifungal agent Candida albicans Benzenic compound Absolute configuration Five membered ring Fluorine Organic compounds Organic hydroxysulfide Nitrogen heterocycle In vitro In vivo Mouse Sulfonamide Triazole derivatives Fungi Imperfecti Fungi Mammalia Rodentia Thallophyta Vertebrata
- Keyword (es)
- Actividad biológica Antifúngico Candida albicans Compuesto bencénico Configuración absoluta Ciclo 5 eslabones Fluor Compuesto orgánico Hidroxisulfuro orgánico Heterociclo nitrógeno In vitro In vivo Ratón Sulfonamida Triazol derivado Fungi Imperfecti Fungi Mammalia Rodentia Thallophyta Vertebrata
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06C Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4059955
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1248/cpb.42.85 
https://dx.doi.org/10.1248/cpb.42.85
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