Synthesis, biotransformation, pharmacokinetics, and antiviral properties of 5-ethyl-5-halo-6-methoxy-5,6-dihydro-2'-deoxyuridine diastereomers
- Author
- CHERAGHALI, A. M; RAKESH KUMAR; WANG, L; KNAUS, E. E; WIEBE, L. I
Univ. Alberta, fac. pharmacy pharmaceutical sci., Edmonton AB T6G 2N8, Canada - Source
Biochemical pharmacology. 1994, Vol 47, Num 9, pp 1615-1625 ; ref : 36 ref
- CODEN
- BCPCA6
- ISSN
- 0006-2952
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs; Physiology, morphology
- Publisher
- Elsevier Science, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Antiviral Broxuridine Herpesvirus hominis In vitro In vivo Métabolisme Métabolite Pharmacocinétique Pyrimidine nucléoside Rat Sensibilité résistance Synthèse chimique Voie intraveineuse Uridine dérivé Alphaherpesvirinae Herpesviridae Mammalia Rodentia Vertebrata Virus
- Keyword (en)
- Animal Antiviral Herpesvirus hominis In vitro In vivo Metabolism Metabolite Pharmacokinetics Pyrimidine nucleoside Rat Sensitivity resistance Chemical synthesis Intravenous administration Alphaherpesvirinae Herpesviridae Mammalia Rodentia Vertebrata Virus
- Keyword (es)
- Animal Antiviral Herpesvirus hominis In vitro In vivo Metabolismo Metabolito Farmacocinética Pirimidina nucleósido Rata Sensibilidad resistencia Síntesis química Vía intravenosa Alphaherpesvirinae Herpesviridae Mammalia Rodentia Vertebrata Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4085779
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/0006-2952(94)90540-1 
https://dx.doi.org/10.1016/0006-2952(94)90540-1
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