Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum
- Author
- GAMAGE, S. A; NISANA TEPSIRI; PRAPON WILAIRAT; WOJCIK, S. J; FIGGITT, D. P; RALPH, R. K; DENNY, W. A
Univ. Auckland, school medicine, cancer res. lab., Auckland, New Zealand - Source
Journal of medicinal chemistry (Print). 1994, Vol 37, Num 10, pp 1486-1494 ; ref : 47 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antiparasitaire Azide Composé aromatique Composé tricyclique Hétérocycle azote In vitro Plasmodium falciparum Réduction chimique Triamine Acridin-9-one(3,6-diamino-9,10-dihydro) Acridine(9-anilino-3,6-diamino) Protozoa Sporozoa
- Keyword (en)
- Biological activity Parasiticid Organic azide Aromatic compound Tricyclic compound Nitrogen heterocycle In vitro Plasmodium falciparum Chemical reduction Triamine Protozoa Sporozoa
- Keyword (es)
- Actividad biológica Antiparasitario Azida orgánica Compuesto aromático Compuesto tricíclico Heterociclo nitrógeno In vitro Plasmodium falciparum Reducción química Triamina Protozoa Sporozoa
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06B Heterocyclic compounds with only one n hetero atom and condensed derivatives
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4111070
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00036a014 
https://dx.doi.org/10.1021/jm00036a014
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