Synthesis of pyridazine acetic acid derivatives possessing aldose reductase inhibitory activity and antioxidant properties
- Author
- COUDERT, P1 ; ALBUISSON, E2 ; BOIRE, J. Y2 ; DUROUX, E3 ; BASTIDE, P3 ; COUQUELET, J1
[1] Fac. pharmacie, lab. chimie thérapeutique, groupe rech. pharmacochimie, 63001 Clermont-Ferrand, France
[2] Fac. médecine, lab. biomathématiques informatique médicale, 63001 Clermont-Ferrand, France
[3] Fac. pharmacie, lab. pharmacologie pharmacie clin., 63001 Clermont-Ferrand, France - Source
European journal of medicinal chemistry. 1994, Vol 29, Num 6, pp 471-477 ; ref : 27 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acide carboxylique Activité biologique Aldehyde reductase Antioxydant Cycle 6 chaînons Cyclisation Hydrazide organique Hétérocycle azote In vitro Inhibiteur enzyme Relation structure activité Pyridazine-1-acétique acide(3-aryl-5-carboxy-5,6-dihydro-6-oxo) Enzyme Oxidoreductases
- Keyword (en)
- Carboxylic acid Biological activity Aldehyde reductase Antioxidant Six membered ring Cyclization Organic hydrazide Nitrogen heterocycle In vitro Enzyme inhibitor Structure activity relation Enzyme Oxidoreductases
- Keyword (es)
- Acido carboxílico Actividad biológica Aldehyde reductase Antioxidante Ciclo 6 eslabones Ciclización Hidrácida orgánica Heterociclo nitrógeno In vitro Inhibidor enzima Relación estructura actividad Enzima Oxidoreductases
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06C Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4131790
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/0223-5234(94)90074-4 
https://dx.doi.org/10.1016/0223-5234(94)90074-4
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