Stereoselective ene reaction of allylsilanes with amino aldehydes. An application to the synthesis of potential HIV-1 protease inhibitors
- Author
- D'ANIELLO, F; MANN, A; MATTII, D; TADDEI, M
Ugo Schiff univ. Firenze, dip. chimica organica, 50121 Firenze, Italy - Source
Journal of organic chemistry. 1994, Vol 59, Num 14, pp 3762-3768 ; ref : 18 ref
- CODEN
- JOCEAH
- ISSN
- 0022-3263
- Scientific domain
- Biochemistry, molecular biology, biophysics; Organic chemistry
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acide Lewis Activité biologique Alcool secondaire Allylation Aminoalcool Aminoaldéhyde Antiviral Composé aromatique Composé bicyclique Diastéréosélectivité Effet stérique Indane dérivé Inhibiteur enzyme Proteinases Virus HIV1 But-3-énoïque acide(2-[3-t-butoxycarbonylamino-2-hydroxy-4-phénylbutyl]-4-phényl) [2-hydroxyindan-1-yl]amide Carbamate(N-[1-benzyl-4-chlorométhyl-2-hydroxypent-4-ényl] O-t-butyl) Phénylalaninal(N-t-butoxycarbonyl) Propène(2-chlorométhyl-3-triméthylsilyl) Enzyme Hydrolases Lentivirinae Retroviridae Virus immunodéficience humaine Virus
- Keyword (en)
- Lewis acid Biological activity Secondary alcohol Allylation Aminoalcohol Aminoaldehyde Antiviral Aromatic compound Bicyclic compound Diastereoselectivity Steric effect Indan derivatives Enzyme inhibitor Proteinases HIV-1 virus Enzyme Hydrolases Lentivirinae Retroviridae Human immunodeficiency virus Virus
- Keyword (es)
- Acido Lewis Actividad biológica Alcohol secundario Alilación Aminoalcohol Aminoaldehído Antiviral Compuesto aromático Compuesto bicíclico Diastereoselectividad Efecto estérico Inhibidor enzima Proteinases HIV-1 virus Enzima Hydrolases Lentivirinae Retroviridae Human immunodeficiency virus Virus
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C05 Alicyclic compounds, terpenoids, prostaglandins, steroids / 001C03C05A Alicyclic compounds
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4137577
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jo00093a006 
https://dx.doi.org/10.1021/jo00093a006
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