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Synthesis and antitumor activity of novel mitomycin derivatives containing functional groups at the C-6-methyl position

Author
ARAI, H; KANDA, Y; ASHIZAWA, T; MORIMOTO, M; GOMI, K; KONO, M; KASAI, M
Kyowa Hakko Kogyo Co., Ltd, Pharmaceutical Research Laboratories, Sunto, Shizuoka 411, Japan
Source

Journal of medicinal chemistry (Print). 1994, Vol 37, Num 12, pp 1794-1804 ; ref : 13 ref

CODEN
JMCMAR
ISSN
0022-2623
Scientific domain
Pharmacology drugs
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Addition Michaël Alcoxylation Animal Antibiotique Anticancéreux Carbamate organique Composé aromatique Composé tétracyclique Hétérocycle azote angulaire In vitro In vivo Quinone Souris Sulfénylation Azirino[2',3':3,4]pyrrolo[1,2-a]indole dérivé Mitomycine A Mitomycine dérivé Mammalia Rodentia Vertebrata
Keyword (en)
Biological activity Michael addition Alkoxylation Animal Antibiotic Antineoplastic agent Organic carbamate Aromatic compound Tetracyclic compound Angular nitrogen heterocycle In vitro In vivo Quinone Mouse Sulfenylation Mammalia Rodentia Vertebrata
Keyword (es)
Actividad biológica Adición Michael Alcoxilación Animal Antibiótico Anticanceroso Carbamato orgánico Compuesto aromático Compuesto tetracíclico Heterociclo nitrógeno angular In vitro In vivo Quinona Ratón Sulfenilación Mammalia Rodentia Vertebrata
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06C Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings

Discipline
Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
4142129

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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