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One-step reduction-Wittig olefination of methyl pyroglutamate : chiral syntheses of (5S)-5-alkenyl-2-pyrrolidinones and (S)-Vigabatrin®

Author
WEI, Z. Y; KNAUS, E. E
Univ. Alberta, fac. pharmacy pharmaceutical sci., Edmonton AB T6G 2N8, Canada
Source

Synlett. 1994, Num 5, pp 345-346

ISSN
0936-5214
Scientific domain
Organic chemistry
Publisher
Thieme, New york, NY / Thieme, Stuttgart
Publication country
Germany
Document type
Article
Language
English
Keyword (fr)
Carbamate organique Composé éthylénique Cycle 5 chaînons Hétérocycle azote Lactame Milieu acide Pyrrolidine dérivé Réaction Wittig Réaction tandem Réduction chimique Vigabatrine α-Aminoacide Phosphorane(méthylène triphényl) Pyroglutamique acide(1-[t-butoxycarbonyl]) ester méthyle Pyrrolidine-1-carboxylique acide(2-oxo-5-vinyl) ester t-butyle
Keyword (en)
Organic carbamate Ethylenic compound Five membered ring Nitrogen heterocycle Lactam Acid medium Pyrrolidine derivatives Wittig reaction Tandem reaction Chemical reduction α-Aminoacid
Keyword (es)
Carbamato orgánico Compuesto etilénico Ciclo 5 eslabones Heterociclo nitrógeno Lactamo Medio ácido Reacción Wittig Reacción tándem Reducción química α-Aminoácido
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06B Heterocyclic compounds with only one n hetero atom and condensed derivatives

Discipline
Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
4156479

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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