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Syntheses and antitumor activities of D- and L-2'-deoxy-4'-thio pyrimidine nucleosides

Author
UENISHI, J1 ; TAKAHASHI, K1 ; MOTOYAMA, M1 ; AKASHI, H; SASAKI, T
[1] Okayama univ. sci. Ridaicho, dep. chemistry, Okayama 700, Japan
Source

Nucleosides & nucleotides. 1994, Vol 13, Num 6-7, pp 1347-1361 ; ref : 18 ref

CODEN
NUNUD5
ISSN
0732-8311
Scientific domain
Biotechnology; Organic chemistry
Publisher
Dekker, Monticello, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Anticancéreux Composé organique Cycle 5 chaînons Diffraction RX Enantiomère Etude expérimentale Hétérocycle soufre In vitro Leucémie L1210 Lignée KB Lignée cellulaire Pyrimidine nucléoside Structure cristalline Structure moléculaire Thioglycoside 4-Thioribofuranoside(5-O-acétyl-3-O-t-butyldiméthylsilyl-1-O-éthyl) Cytosine(1-[2-désoxy-4-thio-érythro-pentofuranosyl]) Pyrimidine2,4-bis[triméthylsiloxy] Thymine(1-[4-thio-érythro-pentofuranosyl]) Uracile(1-[2-désoxy-4-thio-érythro-pentofuranosyl]) Uracile(1-[2-désoxy-4-thio-β-D-érythro-pentofuranosyl]-5-trifluorométhyl) Uracile(1-[5-O-acétyl-2-désoxy-4-thio-α-D-érythro-pentofuranosyl])
Keyword (en)
Biological activity Antineoplastic agent Organic compounds Five membered ring X ray diffraction Enantiomer Experimental study Sulfur heterocycle In vitro L1210-Leukemia KB cell line Cell line Pyrimidine nucleoside Crystalline structure Molecular structure Thioglycoside
Keyword (es)
Actividad biológica Anticanceroso Compuesto orgánico Ciclo 5 eslabones Difracción RX Enantiómero Estudio experimental Heterociclo azufre In vitro Leucemia L1210 Célula KB Línea celular Pirimidina nucleósido Estructura cristalina Estructura molecular Tioglicósido
Classification
Pascal
001 Exact sciences and technology / 001B Physics / 001B60 Condensed matter: structure, mechanical and thermal properties / 001B60A Structure of solids and liquids; crystallography / 001B60A66 Structure of specific crystalline solids / 001B60A66H Organic compounds / 001B60A66H3 Heterocyclic compounds

Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C07 Carbohydrates. Nucleosides and nucleotides / 001C03C07B Nucleosides, nucleotides and oligonucleotides

Pacs
6166H Organic compounds

Discipline
Organic chemistry Physics of condensed state : structure, mechanical and thermal properties
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
4162030

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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