Synthesis and biological activities of a new set of irreversibly acting 2-(4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta
- Author
- SLAVICA, M; LONGPING PEI; PATIL, P. N; KEREZY, A; FELLER, D. R; MILLER, D. D
Ohio State univ., coll. pharmacy, div. medicinal chemistry, Columbus OH 43210, United States - Source
Journal of medicinal chemistry (Print). 1994, Vol 37, Num 12, pp 1874-1881 ; ref : 45 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Animal Aorte thoracique Calcium Canal ionique Fixation biologique In vitro Irréversible Isothiocyanate organique Mécanisme action Rat Relation structure activité Synthèse chimique Vasoconstriction Imidazole(4,5-dihydro-2-[4-isothiocyanatophénéthyl]) Récepteur imidazoline Récepteur non-adrénergique Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Thoracic aorta Calcium Ionic channel Biological fixation In vitro Irreversible Organic isothiocyanate Mechanism of action Rat Structure activity relation Chemical synthesis Vasoconstriction Imidazoline receptor Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Aorta torácica Calcio Canal iónico Fijación biológica In vitro Irreversible Isotiocianato orgánico Mecanismo acción Rata Relación estructura actividad Síntesis química Vasoconstricción Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F09 Miscellaneous
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4198817
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00038a017 
https://dx.doi.org/10.1021/jm00038a017
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