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Synthesis of ISIS 2105 containing the abasic site model compound 1,4-anhydro-2-deoxy-D-ribitol

Author
RAVIKUMAR, V. T; WYRZYKIEWICZ, T. K; COLE, D. L
Isis Pharmaceuticals, Carlsbad CA 92008, United States
Source

Nucleosides & nucleotides. 1994, Vol 13, Num 8, pp 1695-1706 ; ref : 33 ref

CODEN
NUNUD5
ISSN
0732-8311
Scientific domain
Biotechnology; Organic chemistry
Publisher
Dekker, Monticello, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Alditol Analogue Automatisation Dépurination Désoxyribonucléotide Oligodésoxyribonucléotide Oligonucléotide Phase solide Sulfuration Thiophosphate organique Cytidine(N4-benzoyl-2p-désoxy-5p-O-diméthoxytrityl)-3p-phosphoramidite(O-[2-cyanoéthyl]-N,N-diisopropyl) Guanosine(2p-désoxy-5p-O-diméthoxytrityl-N2-isobutyryl)-3p-phosphoramidite(O-[2-cyanoéthyl]-N,N-diisopropyl) ISIS 2105 analogue Ribitol(1,4-anhydro-2-désoxy-5-O-diméthoxytrityl)-3-phosphoramidite(O-[2-(diphényl méthyl silyl)éthyl] N,N-diisopropyl)
Keyword (en)
Alditol Analog Automation Depurination Deoxyribonucleotide Oligodeoxyribonucleotide Oligonucleotide Solid phase Sulfurization Organic thiophosphate
Keyword (es)
Alditol Análogo Automatización Despurinación Desoxirribonucleótido Oligodesoxirribonucleótido Oligonucleótido Fase sólida Sulfurización Tiofosfato orgánico
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C07 Carbohydrates. Nucleosides and nucleotides / 001C03C07A Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides

Discipline
Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
4250278

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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