Functional analogus of CC-1065 and the duocarmycins incorporating the 9a-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (C2BI) alkylation subunit : synthesis and preliminary DNA alkylation studies
- Author
- BOGER, D. L; PALANKI, M. S. S
Scripps res. inst., dep. chemistry, La Jolla CA 92037, United States - Source
Journal of the American Chemical Society. 1992, Vol 114, Num 24, pp 9318-9327 ; ref : 40 ref
- CODEN
- JACSAT
- ISSN
- 0002-7863
- Scientific domain
- Biochemistry, molecular biology, biophysics; Chemistry; Organic chemistry; Atomic molecular physics
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Addition nucléophile Alkylation Chlore Composé organique Composé aromatique Composé tétracyclique DNA Hétérocycle azote Solvolyse CC-1065 analogue Cyclopropa benzo indole dérivé Duocarmycine analogue
- Keyword (en)
- Nucleophilic addition Alkylation Chlorine Organic compounds Aromatic compound Tetracyclic compound DNA Nitrogen heterocycle Solvolysis
- Keyword (es)
- Adición nucleófila Alquilación Cloro Compuesto orgánico Compuesto aromático Compuesto tetracíclico DNA Heterociclo nitrógeno Solvolisis
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06B Heterocyclic compounds with only one n hetero atom and condensed derivatives
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4456794
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/ja00050a012 
https://dx.doi.org/10.1021/ja00050a012
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