An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allow the engineering of a multifunctional pan-neurotrophin
- Author
- IBANEZ, C. F1 ; ILAG, L. L1 ; MURRAY-RUST, J; PERSSON, H1
[1] Karolinska inst., dep. medical chemistry, lab. molecular neurobiology, 104 01 Stockholm, Sweden - Source
EMBO journal (Print). 1993, Vol 12, Num 6, pp 2281-2293 ; ref : 64 ref
- CODEN
- EMJODG
- ISSN
- 0261-4189
- Scientific domain
- Biochemistry, molecular biology, biophysics
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activation métabolique Facteur croissance nerf Facteur croissance Fixation ligand Lignée cellulaire Mutagenèse dirigée Mécanisme action Méthode étude Phosphorylation Polypeptide Protein-tyrosine kinase Rein Récepteur membranaire Singe Transduction signal Facteur neurotrophique encéphale Lignée COS Neurotrophine Enzyme Mammalia Primates Vertebrata
- Keyword (en)
- Metabolic activation Nerve growth factor Growth factor Ligand binding Cell line Site directed mutagenesis Mechanism of action Investigation method Phosphorylation Polypeptide Protein-tyrosine kinase Kidney Membrane receptor Monkey Signal transduction Enzyme Mammalia Primates Vertebrata
- Keyword (es)
- Activación metabólica Factor crecimiento nervio Factor crecimiento Fijación ligando Línea celular Mutagénesis dirigida Mecanismo acción Método estudio Fosforilación Polipéptido Protein-tyrosine kinase Riñón Receptor membrana Mono Transducción señal Enzima Mammalia Primates Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H17 Signal transduction
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4749852
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/j.1460-2075.1993.tb05882.x 
https://dx.doi.org/10.1002/j.1460-2075.1993.tb05882.x
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