Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression
- Author
- MONIA, B. P1 ; LESNIK, E. A; GONZALEZ, C; LIMA, W. F; MCGEE, D; GUINOSSO, C. J; KAWASAKI, A. M; COOK, P. D; FREIER, S. M
[1] ISIS pharmaceuticals, dep. molecular pharmacology, Carlsbad CA 92008, United States - Source
The Journal of biological chemistry (Print). 1993, Vol 268, Num 19, pp 14514-14522 ; ref : 58 ref
- CODEN
- JBCHA3
- ISSN
- 0021-9258
- Scientific domain
- Biochemistry, molecular biology, biophysics; Biotechnology
- Publisher
- American Society for Biochemistry and Molecular Biology, Bethesda, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Inhibition Modification chimique RNA antisens Ribonuclease H Transcription Gène ras Enzyme Oligonucléotide
- Keyword (en)
- Biological activity Inhibition Chemical modification Antisense RNA Ribonuclease H Transcription Enzyme Oligonucleotide
- Keyword (es)
- Actividad biológica Inhibición Modificación química RNA antisentido Ribonuclease H Transcripción Enzima Oligonucleótido
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02C Nucleic acids / 002A02C04 Rna, ribonucleoproteins
- Discipline
- Analytical, structural and metabolic biochemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4839251
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0021-9258(19)85268-7 
https://dx.doi.org/10.1016/S0021-9258(19)85268-7
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