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Facile amide bond formation from esters of amino acids and peptides catalyzed by alkaline protease in an hydrous tert-butyl alcohol using ammonium chloride/triethylamine as a source of nucleophilic ammonia

Author
SHUI-TEIN CHEN1 ; MING-KUEI JANG; KUNG-TSUNG WANG1
[1] Acad. sinica, inst. biological chemistry, lab. biocatalyst, Taipei 10098, Taiwan, Province of China
Source

Synthesis (Stuttgart). 1993, Num 9, pp 858-860 ; ref : 6 ref

CODEN
SYNTBF
ISSN
0039-7881
Scientific domain
Organic chemistry
Publisher
Thieme, New York, NY / Thieme, Stuttgart
Publication country
Germany
Document type
Article
Language
English
Keyword (fr)
Ammonium Chlorure Milieu anhydre Réaction enzymatique Synthèse peptidique Alcalase Leucine(bezyloxycarbonylalanyl-phénylalanyl) amide Triéthylamine t-Butanol α-Aminoacide(N-benzyloxycarbonyl) amide α-Aminoacide(N-benzyloxycarbonyl) ester méthyle
Keyword (en)
Ammonium Chlorides Anhydrous medium Enzymatic reaction Peptide synthesis
Keyword (es)
Amonio Cloruro Medio anhidro Reacción enzimática Síntesis peptídica
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C08 Peptides

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31C Methods. Procedures. Technologies / 002A31C06 Bioconversions. Hemisynthesis

Discipline
Biotechnology Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
4889563

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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