Alteration of the carbohydrate binding specificity of verotoxins from Galα1-4Gal to GalNAcβ1-3Galα1-4Gal and vice versa by site-directed mutagenesis of the binding subunit
- Author
- TYRRELL, G. J1 ; RAMOTAR, K; TOYE, B; LINGWOOD, C. A; BRUNTON, J. L
[1] Samuel Lunenfeld res. inst., mount sinai hosp., Toronto ON M5G 1X5, Canada - Source
Proceedings of the National Academy of Sciences of the United States of America. 1992, Vol 89, Num 2, pp 524-528 ; ref : 32 ref
- CODEN
- PNASA6
- ISSN
- 0027-8424
- Scientific domain
- Multidisciplinary
- Publisher
- National Academy of Sciences of the United States of America, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Capacité fixation Cytotoxicité Escherichia coli Glucide Mutagenèse dirigée Site fixation Souche pathogène Sphingoglycolipide Spécificité Toxine Verotoxine Bactérie Enterobacteriaceae
- Keyword (en)
- Binding capacity Cytotoxicity Escherichia coli Carbohydrate Site directed mutagenesis Binding site Pathogen strain Sphingoglycolipid Specificity Toxin Bacteria Enterobacteriaceae
- Keyword (es)
- Capacidad de fijación Citotoxicidad Escherichia coli Glúcido Mutagénesis dirigida Sitio fijación Cepa patógena Esfingoglicolípido Especificidad Toxina Bacteria Enterobacteriaceae
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05B Bacteriology / 002A05B10 Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 5080853
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1073/pnas.89.2.524 
https://dx.doi.org/10.1073/pnas.89.2.524
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