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Constitutive activation of the α1B-adrenergic receptor by all amino acid substitutions at a single site : evidence for a region which constrains receptor activation

Author
KJELSBERG, M. A; COTECCHIA, S; OSTROWSKI, J; CARON, M. G; LEFKOWITZ, R. J
Duke univ. medical cent., Howard Hughes medical inst., dep. medicine, Durham NC 27710, United States
Source

The Journal of biological chemistry (Print). 1992, Vol 267, Num 3, pp 1430-1433 ; ref : 27 ref

CODEN
JBCHA3
ISSN
0021-9258
Scientific domain
Biochemistry, molecular biology, biophysics; Biotechnology
Publisher
American Society for Biochemistry and Molecular Biology, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activation Capacité fixation Conformation Mutagenèse dirigée Mutation Relation structure activité Récepteur α1-adrénergique Récepteur hormonal
Keyword (en)
Activation Binding capacity Conformation Site directed mutagenesis Mutation Structure activity relation α1-Adrenergic receptor Hormonal receptor
Keyword (es)
Activación Capacidad de fijación Conformación Mutagénesis dirigida Mutación Relación estructura actividad Receptor α1-adrenérgico Receptor hormonal
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04F Cell structures and functions / 002A04F03 Cell receptors / 002A04F03A Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
5203323

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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