A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and/or recurrent squamous cell carcinoma of the head and neck
- Author
- SCHORNAGEL, J. H; VERWEIJ, J; LEFEBVRE, J. L; DE MULDER, P. H. M; COGNETTI, F; VERMORKEN, J. B; CAPPELAERE, P; ARMAND, J. P; WILDIERS, J; CALVEL, M; KIRKPATRICK, A
Netherlands cancer inst., Amsterdam 1066 CX, Netherlands - Source
Annals of oncology. 1992, Vol 3, Num 3, pp 223-226 ; ref : 14 ref
- ISSN
- 0923-7534
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Antifolate Antimétabolite Chimiothérapie Epithélioma spinocellulaire Essai clinique phase II Essai thérapeutique contrôlé Homme Recidive Stade avancé Traitement Tumeur maligne Tête cou Voie intraveineuse ORL pathologie
- Keyword (en)
- Antineoplastic agent Antifolate Antimetabolic Chemotherapy Squamous cell carcinoma Phase II trial Controlled therapeutic trial Human Relapse Advanced stage Treatment Malignant tumor Head and neck Intravenous administration ENT disease
- Keyword (es)
- Anticanceroso Antifolato Antimetabólito Quimioterapia Epitelioma espinocelular Ensayo clínico fase II Ensayo terapéutico controlado Hombre Recaida Estadio avanzado Tratamiento Tumor maligno Cabeza cuello Vía intravenosa ORL patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 5222048
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1093/oxfordjournals.annonc.a058156 
https://dx.doi.org/10.1093/oxfordjournals.annonc.a058156
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:37:\"10.1093\/oxfordjournals.annonc.a058156\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:9:\"\u0000*\u0000jtitle\";s:18:\"Annals of oncology\";s:9:\"\u0000*\u0000stitle\";s:10:\"Ann. oncol\";s:7:\"\u0000*\u0000date\";s:4:\"1992\";s:9:\"\u0000*\u0000volume\";s:1:\"3\";s:8:\"\u0000*\u0000issue\";s:1:\"3\";s:8:\"\u0000*\u0000spage\";s:3:\"223\";s:8:\"\u0000*\u0000epage\";s:3:\"226\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0923-7534\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"SCHORNAGEL\";s:10:\"\u0000*\u0000aufirst\";s:4:\"J. H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:10:\"VERWEIJ, J\";i:1;s:14:\"LEFEBVRE, J. L\";i:2;s:18:\"DE MULDER, P. H. M\";i:3;s:11:\"COGNETTI, F\";i:4;s:15:\"VERMORKEN, J. B\";i:5;s:13:\"CAPPELAERE, P\";i:6;s:12:\"ARMAND, J. P\";i:7;s:11:\"WILDIERS, J\";i:8;s:9:\"CALVEL, M\";i:9;s:14:\"KIRKPATRICK, A\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:23:\"Oxford University Press\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:37:\"10.1093\/oxfordjournals.annonc.a058156\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:9:\"\u0000*\u0000jtitle\";s:18:\"Annals of oncology\";s:9:\"\u0000*\u0000stitle\";s:10:\"Ann. oncol\";s:7:\"\u0000*\u0000date\";s:4:\"1992\";s:9:\"\u0000*\u0000volume\";s:1:\"3\";s:8:\"\u0000*\u0000issue\";s:1:\"3\";s:8:\"\u0000*\u0000spage\";s:3:\"223\";s:8:\"\u0000*\u0000epage\";s:3:\"226\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0923-7534\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"SCHORNAGEL\";s:10:\"\u0000*\u0000aufirst\";s:4:\"J. H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:10:\"VERWEIJ, J\";i:1;s:14:\"LEFEBVRE, J. L\";i:2;s:18:\"DE MULDER, P. H. M\";i:3;s:11:\"COGNETTI, F\";i:4;s:15:\"VERMORKEN, J. B\";i:5;s:13:\"CAPPELAERE, P\";i:6;s:12:\"ARMAND, J. P\";i:7;s:11:\"WILDIERS, J\";i:8;s:9:\"CALVEL, M\";i:9;s:14:\"KIRKPATRICK, A\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:23:\"Oxford University Press\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:37:\"10.1093\/oxfordjournals.annonc.a058156\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:37:\"10.1093\/oxfordjournals.annonc.a058156\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:9:\"\u0000*\u0000jtitle\";s:18:\"Annals of oncology\";s:9:\"\u0000*\u0000stitle\";s:10:\"Ann. oncol\";s:7:\"\u0000*\u0000date\";s:4:\"1992\";s:9:\"\u0000*\u0000volume\";s:1:\"3\";s:8:\"\u0000*\u0000issue\";s:1:\"3\";s:8:\"\u0000*\u0000spage\";s:3:\"223\";s:8:\"\u0000*\u0000epage\";s:3:\"226\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0923-7534\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"SCHORNAGEL\";s:10:\"\u0000*\u0000aufirst\";s:4:\"J. H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:10:\"VERWEIJ, J\";i:1;s:14:\"LEFEBVRE, J. L\";i:2;s:18:\"DE MULDER, P. H. M\";i:3;s:11:\"COGNETTI, F\";i:4;s:15:\"VERMORKEN, J. B\";i:5;s:13:\"CAPPELAERE, P\";i:6;s:12:\"ARMAND, J. P\";i:7;s:11:\"WILDIERS, J\";i:8;s:9:\"CALVEL, M\";i:9;s:14:\"KIRKPATRICK, A\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:23:\"Oxford University Press\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:37:\"10.1093\/oxfordjournals.annonc.a058156\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:9:\"\u0000*\u0000jtitle\";s:18:\"Annals of oncology\";s:9:\"\u0000*\u0000stitle\";s:10:\"Ann. oncol\";s:7:\"\u0000*\u0000date\";s:4:\"1992\";s:9:\"\u0000*\u0000volume\";s:1:\"3\";s:8:\"\u0000*\u0000issue\";s:1:\"3\";s:8:\"\u0000*\u0000spage\";s:3:\"223\";s:8:\"\u0000*\u0000epage\";s:3:\"226\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0923-7534\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"SCHORNAGEL\";s:10:\"\u0000*\u0000aufirst\";s:4:\"J. H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:10:\"VERWEIJ, J\";i:1;s:14:\"LEFEBVRE, J. L\";i:2;s:18:\"DE MULDER, P. H. M\";i:3;s:11:\"COGNETTI, F\";i:4;s:15:\"VERMORKEN, J. B\";i:5;s:13:\"CAPPELAERE, P\";i:6;s:12:\"ARMAND, J. P\";i:7;s:11:\"WILDIERS, J\";i:8;s:9:\"CALVEL, M\";i:9;s:14:\"KIRKPATRICK, A\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:23:\"Oxford University Press\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:37:\"10.1093\/oxfordjournals.annonc.a058156\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:9:\"\u0000*\u0000jtitle\";s:18:\"Annals of oncology\";s:9:\"\u0000*\u0000stitle\";s:10:\"Ann. oncol\";s:7:\"\u0000*\u0000date\";s:4:\"1992\";s:9:\"\u0000*\u0000volume\";s:1:\"3\";s:8:\"\u0000*\u0000issue\";s:1:\"3\";s:8:\"\u0000*\u0000spage\";s:3:\"223\";s:8:\"\u0000*\u0000epage\";s:3:\"226\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0923-7534\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:10:\"SCHORNAGEL\";s:10:\"\u0000*\u0000aufirst\";s:4:\"J. H\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:10:\"VERWEIJ, J\";i:1;s:14:\"LEFEBVRE, J. L\";i:2;s:18:\"DE MULDER, P. H. M\";i:3;s:11:\"COGNETTI, F\";i:4;s:15:\"VERMORKEN, J. B\";i:5;s:13:\"CAPPELAERE, P\";i:6;s:12:\"ARMAND, J. P\";i:7;s:11:\"WILDIERS, J\";i:8;s:9:\"CALVEL, M\";i:9;s:14:\"KIRKPATRICK, A\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:158:\"A phase II trial of 10-ethyl-10-deaza-aminopterin, a novel antifolate, in patients with advanced and\/or recurrent squamous cell carcinoma of the head and neck\";s:8:\"\u0000*\u0000place\";s:6:\"Oxford\";s:6:\"\u0000*\u0000pub\";s:23:\"Oxford University Press\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
