Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
- Author
- BARNES, D. A; FOOTE, S. J; GALATIS, D; KAMP, D. J; COWMAN, A. F
Royal Melbourne hosp., Walter Eliza Hall inst. medical res., Melbourne Victoria 3050, Australia - Source
EMBO journal (Print). 1992, Vol 11, Num 8, pp 3067-3075 ; ref : 32 ref
- CODEN
- EMJODG
- ISSN
- 0261-4189
- Scientific domain
- Biochemistry, molecular biology, biophysics
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amplification Analyse corrélation Antipaludique Chloroquine Expression génique Gène Méfloquine Nombre copie Plasmodium falciparum Sensibilité résistance Gène pfmdr1 Protozoa Sporozoa
- Keyword (en)
- Amplification Correlation analysis Antimalarial Gene expression Gene Copy number Plasmodium falciparum Sensitivity resistance Protozoa Sporozoa
- Keyword (es)
- Amplificación Análisis correlación Antipalúdico Expresión genética Gen Número copia Plasmodium falciparum Sensibilidad resistencia Protozoa Sporozoa
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A11 Protozoa / 002A11C Biochemistry. Physiology. Immunology. Molecular biology
- Discipline
- Protozoa
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 5372926
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/j.1460-2075.1992.tb05378.x 
https://dx.doi.org/10.1002/j.1460-2075.1992.tb05378.x
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