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Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts

Author
LUKASH, L. L1 ; BOLDT, J; PEGG, A. E; DOLAN, M. E; MAHER, V. M; MCCORMICK, J. J
[1] Michigan state univ., dep. microbiology, carcinogenesis lab., East Lansing MI 48824, United States
Source

Mutation research. 1991, Vol 250, Num 1-2, pp 397-409 ; ref : 1 p. 1/2

CODEN
MUREAV
ISSN
0027-5107
Scientific domain
Medical oncology; Genetics
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Keyword (fr)
Agent alkylant Culture cellulaire Fibroblaste Fréquence apparition Guanidine(1-méthyl-2-nitro-1-nitroso) Gène Homme Hypoxanthine phosphoribosyltransferase Mutation Nitramine Nitrosamine Site action Alkylant DNA(guanine-6) alkyltransférase Enzyme
Keyword (en)
Alkylating agent Cell culture Fibroblast Occurrence frequency Gene Human Hypoxanthine phosphoribosyltransferase Mutation Nitroamine Nitrosamine Site of action Enzyme
Keyword (es)
Agente alquilante Cultivo celular Fibroblasto Frecuencia aparición Gen Hombre Hypoxanthine phosphoribosyltransferase Mutación Nitramina Nitrosamina Lugar acción Enzima
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C07 Mutagenesis. Repair

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
5373201

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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