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Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

Author
MOLLOY, S. S1 ; BRESNAHAN, P. A1 ; LEPPLA, S. H; KLIMPEL, K. R; THOMAS, G1
[1] Oregon health sci. univ., vollum inst., Portland OR 97201, United States
Source

The Journal of biological chemistry (Print). 1992, Vol 267, Num 23, pp 16396-16402 ; ref : 45 ref

CODEN
JBCHA3
ISSN
0021-9258
Scientific domain
Biochemistry, molecular biology, biophysics; Biotechnology
Publisher
American Society for Biochemistry and Molecular Biology, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité enzymatique Homme Mutagenèse dirigée Régulation Site clivage Spécificité substrat Furin Enzyme
Keyword (en)
Enzymatic activity Human Site directed mutagenesis Regulation(control) Cleavage site Substrate specificity Enzyme
Keyword (es)
Actividad enzimática Hombre Mutagénesis dirigida Regulación Sitio clivaje Especificidad sustrato Enzima
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E04 Hydrolases

Discipline
Analytical, structural and metabolic biochemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
5566382

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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