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V gene rearrangement is required to fully activate the hypermutation mechanism in B cells

Author
ROES, J1 ; HÜPPI, K; RAJEWSKY, K; SABLITZKY, F
[1] Univ. Cologne, inst. genetics, Cologne 5000, Germany
Source

The Journal of immunology (1950). 1989, Vol 142, Num 3, pp 1022-1026 ; ref : 40 ref

CODEN
JOIMA3
ISSN
0022-1767
Scientific domain
Biochemistry, molecular biology, biophysics; Immunology, immunopathology, allergology
Publisher
American Association of Immunologists, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Anticorps Carte restriction Clonage moléculaire Cytodifférenciation Fréquence Gène Hybridome Immunoglobuline Localisation Locus Lymphocyte B Mutation somatique Mutation Réarrangement génique Région variable Souris Séquence nucléotide Région D Région J Mammalia Rodentia Vertebrata
Keyword (en)
Antibody Restriction map Molecular cloning Cell differentiation Frequency Gene Hybridoma Immunoglobulins Localization Locus B-Lymphocyte Somatic mutation Mutation Gene rearrangement Variable region Mouse Nucleotide sequence Mammalia Rodentia Vertebrata
Keyword (es)
Anticuerpo Mapa restricción Clonación molecular Diferenciación celular Frecuencia Gen Hibridoma Inmunoglobulina Localización Locus Linfocito B Mutación somática Mutación Redisposición génica Región variable Ratón Secuencia nucleótido Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C02 Genes. Genome

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
6641403

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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