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Agonistic antibodies stimulate the kinase encoded by the neu protooncogene in living cells but the oncogenic mutant is constitutively active

Author
YARDEN, Y1
[1] Weizmann inst. sci., dep. chemical immunology, Rehovot 76100, Israel
Source

Proceedings of the National Academy of Sciences of the United States of America. 1990, Vol 87, Num 7, pp 2569-2573 ; ref : 27 ref

CODEN
PNASA6
ISSN
0027-8424
Scientific domain
Multidisciplinary
Publisher
National Academy of Sciences of the United States of America, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Anticorps monoclonal Carcinogenèse Facteur croissance épiderme Gène onc cellulaire Kinase Lignée cellulaire Mutation Méthode immunologique Phosphorylation Produit gène Récepteur biologique Souris Tyrosine Gène neu Mammalia Rodentia Vertebrata
Keyword (en)
Monoclonal antibody Carcinogenesis Epidermal growth factor C-Onc gene Kinase Cell line Mutation Immunological method Phosphorylation Gene product Biological receptor Mouse Tyrosine Mammalia Rodentia Vertebrata
Keyword (es)
Anticuerpo monoclonal Carcinogénesis Factor crecimiento epidermi Gen onc celular Kinase Línea celular Mutación Método inmunológico Fosforilación Producto gene Receptor biológico Ratón Tirosina Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04F Cell structures and functions / 002A04F03 Cell receptors

Discipline
Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
6871759

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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