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Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation human by liver microsomes

Author
OTTON, S. V1 ; CREWE, H. K; LENNARD, M. S; TUCKER, G. T; WOODS, H. F
[1] Univ. Sheffield, royal Hallamshire hosp., dep. pharmacology, Sheffield S10 2JF, United Kingdom
Source

The Journal of pharmacology and experimental therapeutics. 1988, Vol 247, Num 1, pp 242-247 ; ref : 2 p

CODEN
JPETAB
ISSN
0022-3565
Scientific domain
Pharmacology drugs
Publisher
American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Bloquant β-adrénergique Foie Homme In vitro Microsome Métabolisme Métoprolol Oxydation Pharmacogénétique Polymorphisme Métabolisme médicament
Keyword (en)
Beta blocking agent Liver Human In vitro Microsome Metabolism Oxidation Pharmacogenetics Polymorphism
Keyword (es)
Bloqueador β-adrenérgico Hígado Hombre In vitro Microsoma Metabolismo Oxidación Farmacogenética Polimorfismo
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09A Catecholaminergic system

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
7312999

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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