Poor metabolizers at the cytochrome P450 2D6 and 2C19 loci are at increased risk of developing adult acute leukaemia
- Author
- RODDAM, P. L1 ; ROLLINSON, S1 ; KANE, E2 ; ROMAN, E2 ; MOORMAN, A2 ; CARTWRIGHT, R2 ; MORGAN, G. J1
[1] Department of Haematology, University of Leeds, Algernon Firth Building, Leeds, United Kingdom
[2] Leukaemia Research Fund Centre for Clinical Epidemiology, Leeds, United Kingdom - Source
Pharmacogenetics (London). 2000, Vol 10, Num 7, pp 605-615 ; ref : 1 P.1/4
- ISSN
- 0960-314X
- Scientific domain
- Genetics; Pharmacology drugs
- Publisher
- Lippincott Williams and Wilkins, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aigu Cytochrome P450 Facteur risque Gène Homme Leucémie lymphoblastique Leucémie myéloblastique Pharmacogénétique Phénotype hydroxylateur Polymorphisme Cytochrome CYP2C19 Cytochrome CYP2D6 Hémopathie maligne Lymphoprolifératif syndrome
- Keyword (en)
- Acute Cytochrome P450 Risk factor Gene Human Acute lymphocytic leukemia Acute myelocytic leukemia Pharmacogenetics Hydroxylator phenotype Polymorphism Malignant hemopathy Lymphoproliferative syndrome
- Keyword (es)
- Agudo Citocromo P450 Factor riesgo Gen Hombre Leucemia linfoblástica Leucemia mieloblástica Farmacogenética Fenotipo hidroxilador Polimorfismo Hemopatía maligna Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution / 002A07C Classical genetics, quantitative genetics, hybrids / 002A07C03 Human
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Discipline
- Eukaryotes genetics. Biological and molecular evolution General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 823446
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1097/00008571-200010000-00004 
https://dx.doi.org/10.1097/00008571-200010000-00004
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