Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion
- Author
- KONDRAGANTI, Sudha1 ; MOHANAM, Sanjeeva1 ; SAWAYA, Raymond1 ; FULLER, Gregory N3 ; RAO, Jasti S1 ; CHINTALA, Shravan K1 ; KIN, Yoshiaki1 ; JASTI, Sushma L2 ; NIRMALA, Chandrasekar1 ; LAKKA, Sajani S1 ; ADACHI, Yoshiaki1 ; KYRITSIS, Athanassios P2 ; ALI-OSMAN, Francis1
[1] Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, United States
[2] Department of Neuro-Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, United States
[3] Department of Neuropathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, United States - Source
Cancer research (Baltimore). 2000, Vol 60, Num 24, pp 6851-6855 ; ref : 29 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Activité enzymatique Animal Anticancéreux Cellule tumorale DNA antisens Expression génique Gelatinase B Glioblastome Homme In vitro In vivo Invasion Lignée cellulaire établie Mécanisme action Oligonucléotide antisens Plasmide Produit gène RNA messager Souris Sélectivité Transfection Vecteur Voie intracérébrale Matrix metalloproteinase Enzyme Gliome malin Hydrolases Mammalia Metalloendopeptidases Peptidases Rodentia Système nerveux central pathologie Système nerveux pathologie Tumeur maligne Vertebrata
- Keyword (en)
- Biological activity Enzymatic activity Animal Antineoplastic agent Tumor cell Antisense DNA Gene expression Gelatinase B Glioblastoma Human In vitro In vivo Invasion Established cell line Mechanism of action Antisense oligonucleotide Plasmid Gene product Messenger RNA Mouse Selectivity Transfection Vector Intracerebral administration Enzyme Malignant glioma Hydrolases Mammalia Metalloendopeptidases Peptidases Rodentia Central nervous system disease Nervous system diseases Malignant tumor Vertebrata
- Keyword (es)
- Actividad biológica Actividad enzimática Animal Anticanceroso Célula tumoral DNA antisentido Expresión genética Gelatinase B Glioblastoma Hombre In vitro In vivo Invasión Línea celular establecida Mecanismo acción Oligonucleótido antisentido Plasmido Producto gene RNA mensajero Ratón Selectividad Transfección Vector Vía intracerebral Enzima Glioma maligno Hydrolases Mammalia Metalloendopeptidases Peptidases Rodentia Sistema nervosio central patología Sistema nervioso patología Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 849863
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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