Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

Author

MORGAN, Dave¹ ; DIAMOND, David M^{2 3} ; CONNOR, Karen¹ ; HATCHER, Jaime⁷ ; HOPE, Caroline⁷ ; GORDON, Marcia¹ ; ARENDASH, Gary W⁷ ; GOTTSCHALL, Paul E¹ ; UGEN, Kenneth E⁴ ; DICKEY, Chad⁴ ; HARDY, John⁵ ; DUFF, Karen⁶ ; JANTZEN, Paul¹ ; DICARLO, Glovanni¹ ; WILCOCK, Donna¹
[1] Alzheimer Research Laboratory, Department of Pharmacology, University of South Florida, Tampa, Florida 33612, United States
[2] Department of Psychology, University of South Florida, Tampa, Florida 33612, United States
[3] James A. Haley VA Center, Tampa, Florida 33612, United States
[4] Department of Medical Microbiology and Immunology, University of South Florida, Tampa, Florida 33612, United States
[5] Department of Pharmacology, Mayo Clinic, Jacksonville, Florida 32224, United States
[6] Nathan Kline Institute, Orangeburg, New York 10962, United States
[7] Alzheimer Research Laboratory, Department of Biology, University of South Florida, Tampa, Florida 33612, United States

Source

Nature (London). 2000, Vol 408, Num 6815, pp 982-985 ; ref : 19 ref

CODEN

NATUAS

ISSN

0028-0836

Scientific domain

Multidisciplinary

Publisher

Nature Publishing, London

Publication country

United Kingdom

Document type

Article

Language

English

Keyword (fr)

Animal transgénique Démence Alzheimer Modèle animal Protéine amyloïde β Prévention Souris Traitement Trouble mémoire Vaccination Encéphale pathologie Maladie dégénérative Mammalia Rodentia Système nerveux central pathologie Système nerveux pathologie Trouble cognition Vertebrata

Keyword (en)

Transgenic animal Alzheimer disease Animal model β Amyloid protein Prevention Mouse Treatment Memory disorder Vaccination Cerebral disorder Degenerative disease Mammalia Rodentia Central nervous system disease Nervous system diseases Cognitive disorder Vertebrata

Keyword (es)

Animal transgénico Demencia Alzheimer Modelo animal Proteína amiloide β Prevención Ratón Tratamiento Trastorno memoria Vacunación Encéfalo patología Enfermedad degenerativa Mammalia Rodentia Sistema nervosio central patología Sistema nervioso patología Trastorno cognitivo Vertebrata

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Discipline

Neurology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

873396

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS