Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
- Author
- LAVAUTE, Timothy1 ; SMITH, Sophia1 ; SWITZER, Robert III4 ; GRINBERG, Alexander5 ; LOVE, Paul5 ; TRESSER, Nancy6 ; ROUAULT, Tracey A1 ; COOPERMAN, Sharon1 ; IWAI, Kazuhiro1 ; LAND, William1 ; MEYRON-HOLTZ, Esther1 ; DRAKE, Steven K1 ; MILLER, Georgina2 ; ABU-ASAB, Mones3 ; TSOKOS, Maria3
[1] Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, Bethesda, Maryland, United States
[2] Veterinary Resources Program, Office of the Director, National Institutes of Health, Bethesda, Maryland, United States
[3] Division of Clinical Sciences, National Cancer Institute, Bethesda Maryland, United States
[4] NeuroScience Associates, Knoxville, Tennessee, United States
[5] Laboratory of Mammalian Genetics and Development, National Institute of Child Health and Human Development, Bethesda, Maryland, United States
[6] Neuroimmunology Branch, National Institute of Neurologic Disease and Stroke, Bethesda Maryland, United States - Source
Nature genetics. 2001, Vol 27, Num 2, pp 209-214 ; ref : 30 ref
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Ciblage Expression génique Fer Gène Mutation Métabolisme Protéine Régulation Souris Mammalia Rodentia Vertebrata
- Keyword (en)
- Targeting Gene expression Iron Gene Mutation Metabolism Protein Regulation(control) Mouse Mammalia Rodentia Vertebrata
- Keyword (es)
- Blancado Expresión genética Hierro Gen Mutación Metabolismo Proteína Regulación Ratón Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C02 Genes. Genome
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 912299
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/84859 
https://dx.doi.org/10.1038/84859
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