Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds
- Author
- PELEKIS, M1 ; GEPHART, L. A1 ; LERMAN, S. E2
[1] Toxicology and Environmental Sciences Division, ExxonMobil Biomedical Sciences, Inc., P.O. Box 971, 1545 Route 22 East, Annandale, New Jersey 08801-0971, United States
[2] Occupational & Public Health Division, ExxonMobil Biomedical Sciences, Inc., P.O. Box 971, 1545 Route 22 East, Annandale, New Jersey 08801-0971, United States - Source
Regulatory toxicology and pharmacology (Print). 2001, Vol 33, Num 1, pp 12-20 ; ref : 23 ref
- CODEN
- RTOPDW
- ISSN
- 0273-2300
- Scientific domain
- Toxicology
- Publisher
- Elsevier, San Diego, CA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adulte Comparaison interindividuelle Comparaison intraspécifique Composé organique volatil Développement foetal Développement postnatal Enfant Incertitude Modèle PBPK Pharmacocinétique Toxicité Toxicocinétique Homme
- Keyword (en)
- Adult Interindividual comparison Intraspecific comparison Volatile organic compound Fetal development Postnatal development Child Uncertainty Physiologically based pharmacokinetic model Pharmacokinetics Toxicity Toxicokinetics Human
- Keyword (es)
- Adulto Comparación interindividual Comparación intraespecífica Compuesto orgánico volátil Desarrollo fetal Desarrollo postnatal Niño Incertidumbre PBPK modelo Farmacocinética Toxicidad Toxicocinética Hombre
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03L Chemical and industrial products toxicology. Toxic occupational diseases / 002B03L06 Various organic compounds
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 950439
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1006/rtph.2000.1436 
https://dx.doi.org/10.1006/rtph.2000.1436
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