A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
- Author
- RAAMSDONK, Léonie M1 ; TEUSINK, Bas1 ; WESTERHOFF, Hans V1 6 ; VAN DAM, Karel1 ; OLIVER, Stephen G3 ; BROADHURST, David2 ; NIANSHU ZHANG3 ; HAYES, Andrew3 ; WALSH, Michael C1 ; BERDEN, Jan A1 ; BRINDLE, Kevin M4 ; KELL, Douglas B2 ; ROWLAND, Jem J5
[1] Swammerdam Institute for Life Sciences, BioCentrum Amsterdam, University of Amsterdam, Plantage Muidergracht 12, 1018 TV Amsterdam, Netherlands
[2] Institute of Biological Sciences, Cledwyn Building, University of Wales, Aberystwyth, Aberystwyth SY23 3DD, United Kingdom
[3] School of Biological Sciences, University of Manchester, 2.205 Stopford Building, Oxford Road, Manchester M13 9PT, United Kingdom
[4] Department of Biochemistry, University of Cambridge, Old Addenbrooke's Site, 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom
[5] Department of Computer Science University of Wales, Aberystwyth, Aberystwyth SY23 3DB, United Kingdom
[6] Department of Molecular Cell Physiology, BioCentrum Amsterdam, Free University, De Boelelaan 1087, 1081 HV, Amsterdam, Netherlands - Source
Nature biotechnology. 2001, Vol 19, Num 1, pp 45-50 ; ref : 54 ref
- CODEN
- NABIF9
- ISSN
- 1087-0156
- Scientific domain
- Biotechnology
- Publisher
- Nature, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Allèle silencieux Analyse fonctionnelle Gène Levure Métabolisme Phénotype Saccharomyces cerevisiae Génomique Métabolome Ascomycetes Fungi Thallophyta
- Keyword (en)
- Silent allele Functional analysis Gene Yeast Metabolism Phenotype Saccharomyces cerevisiae Genomics Metabolome Ascomycetes Fungi Thallophyta
- Keyword (es)
- Alelo silencioso Análisis funcional Gen Levadura Metabolismo Fenotipo Saccharomyces cerevisiae Ascomycetes Fungi Thallophyta
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05D Mycology / 002A05D04 Growth, nutrition, metabolism, transports, enzymes. Molecular biology
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 955898
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/83496 
https://dx.doi.org/10.1038/83496
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