2'-O, 4'-C-methylene bridged nucleic acid (2', 4'-BNA) : Synthesis and triplex-forming properties
- Author
- OBIKA, Satoshi1 ; UNEDA, Takeshi1 ; SUGIMOTO, Tomomi1 ; NANBU, Daishu1 ; MINAMI, Takashi1 ; DOI, Takefumi1 ; IMANISHI, Takeshi1
[1] Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan - Source
Bioorganic & medicinal chemistry. 2001, Vol 9, Num 4, pp 1001-1011 ; ref : 38 ref
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Composé bicyclique DNA bicaténaire Fixation biologique Hybridation moléculaire Hétérocycle oxygène Inhibition Oligonucléotide antisens Phase solide Phosphoramidite organique Protéine liaison DNA Pyrimidine nucléotide RNA antisens Rigidité moléculaire Synthèse chimique Triplet 2,5-Dioxabicyclo[2.2.1]heptane dérivé Dioxabicycloheptane Facteur transcription NFκB Uridine analogue
- Keyword (en)
- Biological activity Bicyclic compound Double stranded DNA Biological fixation Molecular hybridization Oxygen heterocycle Inhibition Antisense oligonucleotide Solid phase Organic phosphoramidite DNA binding protein Pyrimidine nucleotide Antisense RNA Molecular rigidity Chemical synthesis Triplet Transcription factor NFκB
- Keyword (es)
- Actividad biológica Compuesto bicíclico DNA bicatenario Fijación biológica Hibridación molecular Heterociclo oxígeno Inhibición Oligonucleótido antisentido Fase sólida Fosforamidito orgánico Proteína enlace DNA Pirimidina nucleótido RNA antisentido Rigidez molecular Síntesis química Triplete
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 968417
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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