Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic OligonucleotidesKANDIMALLA, Ekambar R; AGRAWAL, Sudhir.Advances in polymer science (Print). 2012, Vol 249, pp 61-94, issn 0065-3195, 34 p.Article

Antisense and siRNA as agonists of Toll-like receptorsAGRAWAL, Sudhir; KANDIMALLA, Ekambar R.Nature biotechnology. 2004, Vol 22, Num 12, pp 1533-1537, issn 1087-0156, 5 p.Article

Antisense anti-MDM2 oligonucleotides as a novel approach to the treatment of glioblastoma multiformePRASAD, Gautam; HUI WANG; AGRAWAL, Sudhir et al.Anticancer research. 2002, Vol 22, Num 1A, pp 107-116, issn 0250-7005Article

Antisense MDM2 oligonucleotides restore the apoptotic response of prostate cancer cells to androgen deprivationZHAOMEI MU; HACHEM, Paul; AGRAWAL, Sudhir et al.The Prostate. 2004, Vol 60, Num 3, pp 187-196, issn 0270-4137, 10 p.Article

Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed-backbone antisense oligonucleotides: In vitro and in vivo activities and mechanismsHUI WANG; DONG YU; AGRAWAL, Sudhir et al.The Prostate. 2003, Vol 54, Num 3, pp 194-205, issn 0270-4137, 12 p.Article

Oral administration of a synthetic agonist of toll-like receptor 9 potently modulates peanut-induced allergy in miceZHU, Fu-Gang; KANDIMALLA, Ekambar R; DONG YU et al.Journal of allergy and clinical immunology. 2007, Vol 120, Num 3, pp 631-637, issn 0091-6749, 7 p.Article

Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides : Structure-immunostimulatory activity relationshipsKANDIMALLA, Ekambar R; DONG YU; QIUYAN ZHAO et al.Bioorganic & medicinal chemistry. 2001, Vol 9, Num 3, pp 807-813, issn 0968-0896Article

Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer : In vitro and in vivo activities and mechanismsHUI WANG; LI NAN; DONG YU et al.Clinical cancer research. 2001, Vol 7, Num 11, pp 3613-3624, issn 1078-0432Article

Oligodeoxynucleotides containing synthetic immunostimulatory motifs augment potent Th1 immune responses to HBsAg in miceYUKUI LI; KANDIMALLA, Ekambar R; DONG YU et al.International immunopharmacology. 2005, Vol 5, Num 6, pp 981-991, issn 1567-5769, 11 p.Article

Accessible 5'-end of CpG-containing phosphorothioate oligodeoxynucleotides is essential for immunostimulatory activityDONG YU; QIUYAN ZHAO; KANDIMALLA, Ekambar R et al.Bioorganic & medicinal chemistry letters (Print). 2000, Vol 10, Num 23, pp 2585-2588, issn 0960-894XArticle

Modifications Incorporated in CpG Motifs of Oligodeoxynucleotides Lead to Antagonist Activity of Toll-Gke Receptors 7 and 9DONG YU; DAQING WANG; ZHU, Fu-Gang et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 16, pp 5108-5114, issn 0022-2623, 7 p.Article

Oligodeoxyribonucleotide-Based Antagonists for Toll-Like Receptors 7 and 9DAQING WANG; BHAGAT, Lakshmi; DONG YU et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 2, pp 551-558, issn 0022-2623, 8 p.Article

Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathwayZHUO ZHANG; HUI WANG; MAO LI et al.Oncogene (Basingstoke). 2005, Vol 24, Num 48, pp 7238-7247, issn 0950-9232, 10 p.Article

Antisense oligonucleotide targeted to RIα subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: in vivo synergistic activity, pharmacokinetics and host toxicityHUI WANG; JIE HANG; ZHENQI SHI et al.International journal of oncology. 2002, Vol 21, Num 1, pp 73-80, issn 1019-6439Article

PKA knockdown enhances cell killing in response to radiation and androgen deprivationHENSLEY, Harvey H; HANNOUN-LEVI, Jean-Michel; HACHEM, Paul et al.International journal of cancer (Print). 2011, Vol 128, Num 4, pp 962-973, issn 0020-7136, 12 p.Article

Toll-like Receptor 9 Agonist IMO Cooperates with Cetuximab in K-Ras Mutant Colorectal and Pancreatic CancersROSY, Roberta; MELISI, Davide; TORTORA, Giampaolo et al.Clinical cancer research (Print). 2011, Vol 17, Num 20, pp 6531-6541, issn 1078-0432, 11 p.Article

Requirement of nucleobase proximal to CpG dinucleotide for immunostimulatory activity of synthetic CpG DNADONG YU; KANDIMALLA, Ekambar R; QIUYAN ZHAO et al.Bioorganic & medicinal chemistry. 2003, Vol 11, Num 3, pp 459-464, issn 0968-0896, 6 p.Article

Design, synthesis, and immunostimulatory properties of CpG DNAs containing alkyl-linker substitutions: Role of nucleosides in the flanking sequencesDONG YU; KANDIMALLA, Ekambar R; YANPING CONG et al.Journal of medicinal chemistry (Print). 2002, Vol 45, Num 20, pp 4540-4548, issn 0022-2623, 9 p.Article

Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis and cooperate with cytotoxic drugs in human cancer cell linesCIARDIELLO, Fortunato; CAPUTO, Rosa; TROIANI, Teresa et al.International journal of cancer. 2001, Vol 93, Num 2, pp 172-178, issn 0020-7136Article

Synthetic oligoribonucleotides containing arabinonucleotides act as agonists of TLR7 and 8TAO LAN; BHAGAT, Lakshmi; DAQING WANG et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 7, pp 2044-2047, issn 0960-894X, 4 p.Article

Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activityDAQING WANG; KANDIMALLA, Ekambar R; DONG YU et al.Vaccine. 2005, Vol 23, Num 20, pp 2614-2622, issn 0264-410X, 9 p.Article

Modulation of ovalbumin-induced Th2 responses by second-generation immunomodulatory oligonucleotides in miceZHU, Fu-Gang; KANDIMALLA, Ekambar R; DONG YU et al.International immunopharmacology. 2004, Vol 4, Num 7, pp 851-862, issn 1567-5769, 12 p.Article

Immunostimulatory activity of CpG oligonucleotides containing non-ionic methylphosphonate linkagesDONG YU; KANDIMALLA, Ekambar R; QIUYAN ZHAO et al.Bioorganic & medicinal chemistry. 2001, Vol 9, Num 11, pp 2803-2808, issn 0968-0896Article

Toll-like Receptor 7 Selective Synthetic Oligoribonucleotide Agonists: Synthesis and Structure—Activity Relationship StudiesTAO LAN; MEIRU DAI; DAQING WANG et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 21, pp 6871-6879, issn 0022-2623, 9 p.Article

Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifsDAQING WANG; YUKUI LI; DONG YU et al.International journal of oncology. 2004, Vol 24, Num 4, pp 901-908, issn 1019-6439, 8 p.Article