Innovation in Therapeutics Development at the NCATSCOLVIS, Christine M; AUSTIN, Christopher P.Neuropsychopharmacology (New York, NY). 2014, Vol 39, Num 1, pp 230-232, issn 0893-133X, 3 p.Article

Foundation review: The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platformSHUKLA, Sunita J; RUILI HUANG; AUSTIN, Christopher P et al.Drug discovery today. 2010, Vol 15, Num 23-24, pp 997-1007, issn 1359-6446, 11 p.Article

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutationMORRIS, Jill A; KANDPAL, Geeta; LEI MA et al.Human molecular genetics (Print). 2003, Vol 12, Num 13, pp 1591-1608, issn 0964-6906, 18 p.Article

Repurposing Approved and Abandoned Drugs for the Treatment and Prevention of Cancer through Public―Private PartnershipWEIR, Scott J; DEGENNARO, Louis J; AUSTIN, Christopher P et al.Cancer research (Chicago, Ill.). 2012, Vol 72, Num 5, pp 1055-1058, issn 0008-5472, 4 p.Article

Evaluation of Substituted N,N'-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate KinaseBOXER, Matthew B; JIANG, Jian-Kang; INGLESE, James et al.Journal of medicinal chemistry (Print). 2010, Vol 53, Num 3, pp 1048-1055, issn 0022-2623, 8 p.Article

Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatBMOTT, Bryan T; FERREIRA, Rafaela S; MCKERROW, James H et al.Journal of medicinal chemistry (Print). 2010, Vol 53, Num 1, pp 52-60, issn 0022-2623, 9 p.Article

Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological ActivityJUDSON, Richard S; MARTIN, Matthew T; AUSTIN, Christopher P et al.Environmental science & technology. 2010, Vol 44, Num 15, pp 5979-5985, issn 0013-936X, 7 p.Article

Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFκB activity within two separate high-throughput screens of NFκB activationYULI XIE; SHIXIAN DENG; AULNER, Nathalie et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 1, pp 329-335, issn 0960-894X, 7 p.Article

Structure Based Model for the Prediction of Phospholipidosis Induction Potential of Small MoleculesHONGMAO SUN; SHAHANE, Sampada; MENGHANG XIA et al.Journal of chemical information and modeling. 2012, Vol 52, Num 7, pp 1798-1805, issn 1549-9596, 8 p.Article

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channelsMENGHANG XIA; SHAHANE, Sampada A; AUSTIN, Christopher P et al.Toxicology and applied pharmacology. 2011, Vol 252, Num 3, pp 250-258, issn 0041-008X, 9 p.Article

Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidaseSHI, Zhen-Dan; MOTABAR, Omid; GOLDIN, Ehud et al.Analytical & bioanalytical chemistry (Print). 2009, Vol 394, Num 7, pp 1903-1909, issn 1618-2642, 7 p.Article

Structure Mechanism Insights and the Role of Nitric Oxide Donation Guide the Development of Oxadiazole-2-Oxides as Therapeutic Agents against SchistosomiasisRAI, Ganesha; STAYED, Ahmed A; AUSTIN, Christopher P et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 20, pp 6474-6483, issn 0022-2623, 10 p.Article

High-Throughput Giardia lamblia Viability Assay Using Bioluminescent ATP Content MeasurementsCHEN, Catherine Z; KULAKOVA, Liudmila; SOUTHALL, Noel et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 2, pp 667-675, issn 0066-4804, 9 p.Article

Quantitative Analyses of Aggregation, Autofluorescence, and Reactivity Artifacts in a Screen for Inhibitors of a Thiol ProteaseJADHAV, Ajit; FERREIRA, Rafaela S; KLUMPP, Carleen et al.Journal of medicinal chemistry (Print). 2010, Vol 53, Num 1, pp 37-51, issn 0022-2623, 15 p.Article

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitorsSKOUMBOURDIS, Amanda P; LECLAIR, Christopher A; MICHNICK, Stephen W et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 13, pp 3686-3692, issn 0960-894X, 7 p.Article

A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophyKANG ZHANG; KNIAZEVA, Marina; KAKUK, Laura E et al.Nature genetics. 2001, Vol 27, Num 1, pp 89-93, issn 1061-4036Article

Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening ApproachSHUKLA, Sunita J; RUILI HUANG; SIMMONS, Steven O et al.Environmental health perspectives. 2012, Vol 120, Num 8, pp 1150-1156, issn 0091-6765, 7 p.Article

Identification of Clinically Used Drugs That Activate Pregnane X ReceptorsSHUKLA, Sunita J; SAKAMURU, Srilatha; RUILI HUANG et al.Drug metabolism and disposition. 2011, Vol 39, Num 1, pp 151-159, issn 0090-9556, 9 p.Article

Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of actionMILLER, Susanne C; RUILI HUANG; SAKAMURU, Srilatha et al.Biochemical pharmacology. 2010, Vol 79, Num 9, pp 1272-1280, issn 0006-2952, 9 p.Article

Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK InhibitionZHEN WANG; MIN ZHENG; WEI ZHENG et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 16, pp 6556-6564, issn 0008-5472, 9 p.Article

Fluorescence Spectroscopic Profiling of Compound LibrariesSIMEONOV, Anton; JADHAV, Ajit; INGLESE, James et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 8, pp 2363-2371, issn 0022-2623, 9 p.Article

A high-throughput screen for aggregation-based inhibition in a large compound libraryFENG, Brian Y; SIMEONOV, Anton; JADHAV, Ajit et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 10, pp 2385-2390, issn 0022-2623, 6 p.Article

DISCI (disrupted in Schizophrenia-I) is expressed in limbic regions of the primate brainAUSTIN, Christopher P; LEI MA; KY, Betty et al.Neuroreport (Oxford). 2003, Vol 14, Num 7, pp 951-954, issn 0959-4965, 4 p.Article

Melanin-concentrating hormone receptor subtypes 1 and 2: Species-specific gene expressionTAN, Carina P; SANO, Hideki; AUSTIN, Christopher P et al.Genomics (San Diego, Calif.). 2002, Vol 79, Num 6, pp 785-792, issn 0888-7543Article

Expression of the cysteinyl leukotriene 1 receptor in normal human lung and peripheral blood leukocytesFIGUEROA, David J; BREYER, Richard M; JONES, Thomas R et al.American journal of respiratory and critical care medicine. 2001, Vol 163, Num 1, pp 226-233, issn 1073-449XArticle