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Up-regulation of ORL-1 receptors in spinal tissue of allodynic rats after sciatic nerve injuryBRISCINI, Luca; CORRADINI, Laura; ONGINI, Ennio et al.European journal of pharmacology. 2002, Vol 447, Num 1, pp 59-65, issn 0014-2999Article

The putative OP4 antagonist, [Nphe1]nociceptin(1-13)NH2, prevents the effects of nociceptin in neuropathic ratsCORRADINI, Laura; BRISCINI, Luca; ONGINI, Ennio et al.Brain research. 2001, Vol 905, Num 1-2, pp 127-133, issn 0006-8993Article

Evidence for a role of melanocortin system in modulation of neuropathic painFREDDUZZI, Silva; REGGIANI, Angelo; BERTORELLI, Rosalia et al.Recent developments in pain research. 2005, pp 229-245, isbn 81-308-0012-8, 1Vol, 17 p.Book Chapter

Melanocortin receptor agonists and antagonists modulate nociceptive sensitivity in the mouse formalin testBELLASIO, Sara; NICOLUSSI, Elisa; BERTORELLI, Rosalia et al.European journal of pharmacology. 2003, Vol 482, Num 1-3, pp 127-132, issn 0014-2999, 6 p.Article

Effects of A1 and A2A adenosine receptor ligands in mouse acute models of painBASTIA, Elena; VARANI, Katia; MONOPOLI, Angela et al.Neuroscience letters. 2002, Vol 328, Num 3, pp 241-244, issn 0304-3940Article

Nociceptin attenuates opioid and γ-aminobutyric acidB receptor-mediated analgesia in the mouse tail-flick assayCITTERIO, Francesca; CORRADINI, Laura; SMITH, Richard D et al.Neuroscience letters. 2000, Vol 292, Num 2, pp 83-86, issn 0304-3940Article

Endogenous and exogenous melanocortin antagonists induce anti-allodynic effects in a model of rat neuropathic painBERTORELLI, Rosalia; FREDDUZZI, Silva; TAROZZO, Glauco et al.Behavioural brain research. 2005, Vol 157, Num 1, pp 55-62, issn 0166-4328, 8 p.Article

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents : a comparison of efficacy and side-effect profilesVARTY, Geoffrey B; GRILLI, Mariagrazia; PARKER, Eric M et al.Psychopharmacologia. 2005, Vol 179, Num 1, pp 207-217, issn 0033-3158, 11 p.Article

A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist propertiesSASIKUMAR, T. K; LI QIANG; BURNETT, Duane A et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 8, pp 2474-2477, issn 0960-894X, 4 p.Article

Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic painSASIKUMAR, T. K; LI QIANG; REGGIANI, Angelo et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 12, pp 3199-3203, issn 0960-894X, 5 p.Article

Identification of single nucleotide polymorphisms of the human metabotropic glutamate receptor 1 gene and pharmacological characterization of a P993S variantDOWNEY, Patrick M; PETRO, Roberta; SIMON, Jason S et al.Biochemical pharmacology. 2009, Vol 77, Num 7, pp 1246-1253, issn 0006-2952, 8 p.Article

The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the ratMELANI, Alessia; PANTONI, Leonardo; BORDONI, Francesca et al.Brain research. 2003, Vol 959, Num 2, pp 243-250, issn 0006-8993, 8 p.Article

Studies on the antinociceptive effect of [Nphe1]nociceptin(1-13)NH2 in miceDI GIANNUARIO, Amalia; RIZZI, Anna; PIERETTI, Stefano et al.Neuroscience letters. 2001, Vol 316, Num 1, pp 25-28, issn 0304-3940Article

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 2BRUMFIELD, Stephanie; MATASI, Julius J; BERTORELLI, Rosalia et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 24, pp 7287-7290, issn 0960-894X, 4 p.Article

3H-[1,2,4] -Triazolo[5,1-i]purin -5 -amine derivatives as adenosine A2A antagonistsSILVERMAN, Lisa S; CALDWELL, John P; ONGINI, Ennio et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 6, pp 1659-1662, issn 0960-894X, 4 p.Article

Potent, selective, and orally active adenosine A2A receptor antagonists : Arylpiperazine derivatives of pyrazolo[4,3-e]-1,2,4-triazolo[1 ,5-c]pyrimidinesNEUSTADT, Bernard R; JINSONG HAO; FOSTER, Carolyn et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 5, pp 1376-1380, issn 0960-894X, 5 p.Article

Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic painWU, Wen-Lian; BURNETT, Duane A; DOMALSKI, Martin et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 23, pp 5550-5553, issn 0022-2623, 4 p.Article

Gene expression profiling of melanocortin system in neuropathic rats supports a role in nociceptionBELTRAMO, Massimiliano; CAMPANELLA, Marilena; TAROZZO, Glauco et al.Molecular brain research. 2003, Vol 118, Num 1-2, pp 111-118, issn 0169-328X, 8 p.Article

Adenosine A2A receptor antagonists are potential antidepressants : evidence based on pharmacology and A2A receptor knockout miceEL YACOUBI, Malika; LEDENT, Catherine; PARMENTIER, Marc et al.British journal of pharmacology. 2001, Vol 134, Num 1, pp 68-77, issn 0007-1188Article

Fused tricyclic mGluR1 antagonists for the treatment of neuropathic painBENNETT, Chad E; BURNETT, Duane A; GRILLI, Mariagrazia et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 4, pp 1575-1578, issn 0960-894X, 4 p.Article

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 1MATASI, Julius J; BRUMFIELD, Stephanie; BERTORELLI, Rosalia et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 12, pp 3805-3808, issn 0960-894X, 4 p.Article

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain modelsSASSO, Oscar; MORENO-SANZ, Guillermo; BERTORELLI, Rosalia et al.Pain (Amsterdam). 2013, Vol 154, Num 3, pp 350-360, issn 0304-3959, 11 p.Article

Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic painBRUMFIELD, Stephanie; KORAKAS, Peter; WU, Wen-Lian et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 23, pp 7223-7226, issn 0960-894X, 4 p.Article

Potent and selective adenosine A2A receptor antagonists : 1,2,4-Triazolo[1,5-c]pyrimidinesNEUSTADT, Bernard R; HONG LIU; FREDDUZZI, Silva et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 3, pp 967-971, issn 0960-894X, 5 p.Article

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