Mass balance studies, with a focus on anticancer drugsBEUMER, Jan H; BEIJNEN, Jos H; SCHELLENS, Jan H. M et al.Clinical pharmacokinetics. 2006, Vol 45, Num 1, pp 33-58, issn 0312-5963, 26 p.Article

Phase I Pharmacokinetic Study of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor Vatalanib (PTK787) Plus Imatinib and Hydroxyurea for Malignant GliomaREARDON, David A; EGORIN, Merrill J; DESJARDINS, Annick et al.Cancer. 2009, Vol 115, Num 10, pp 2188-2198, issn 0008-543X, 11 p.Article

A liquid chromatography-electrospray ionization tandem mass spectrometric assay for quantitation of the histone deacetylase inhibitor, vorinostat (suberoylanilide hydroxamicacid, SAHA), and its metabolites in human serumPARISE, Robert A; HOLLERAN, Julianne L; BEUMER, Jan H et al.Journal of chromatography. B. 2006, Vol 840, Num 2, pp 108-115, issn 1570-0232, 8 p.Article

Disposition of imatinib and its metabolite CGP74588 in a patient with chronic myelogenous leukemia and short-bowel syndromeBEUMER, Jan H; NATALE, James J; LAGATTUTA, Theodore E et al.Pharmacotherapy. 2006, Vol 26, Num 7, pp 903-907, issn 0277-0008, 5 p.Article

Liquid chromatography-mass spectrometric assay for the quantitation in human plasma of ABT-888, an orally available, small molecule inhibitor of poly(ADP-ribose) polymerasePARISE, Robert A; SHAWAQFEH, Mohammad; EGORIN, Merrill J et al.Journal of chromatography. B. 2008, Vol 872, Num 1-2, pp 141-147, issn 1570-0232, 7 p.Article

Quantitative determination of zebularine (NSC 309132), a DNA methyltransferase inhibitor, and three metabolites in murine plasma by high-performance liquid chromatography coupled with on-line radioactivity detectionBEUMER, Jan H; JOSEPH, Erin; EGORIN, Merrill J et al.Journal of chromatography. B. 2006, Vol 831, Num 1-2, pp 147-155, issn 1570-0232, 9 p.Article

Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma linesPARISE, Robert A; ANYANG, Bean N; EISEMAN, Julie L et al.Cancer chemotherapy and pharmacology. 2013, Vol 71, Num 1, pp 73-83, issn 0344-5704, 11 p.Article

Translational Phase I Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytarabine and Etoposide in Patients with Relapsed, Refractory, or High-Risk Acute Myeloid LeukemiaGOJO, Ivana; MING TAN; ESPINOZA-DELGADO, Igor et al.Clinical cancer research (Print). 2013, Vol 19, Num 7, pp 1838-1851, issn 1078-0432, 14 p.Article

A Phase I clinical trial of the combination of imatinib and paclitaxel in patients with advanced or metastatic solid tumors refractory to standard therapyPISHVAIAN, Michael J; SLACK, Rebecca; FIROZVI, Kashif et al.Cancer chemotherapy and pharmacology. 2012, Vol 70, Num 6, pp 843-853, issn 0344-5704, 11 p.Article

Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasmaPARISE, Robert A; BEUMER, Jan H; KANGANI, Cyrous O et al.Journal of chromatography. B. 2008, Vol 862, Num 1-2, pp 168-174, issn 1570-0232, 7 p.Article

ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 TherapyFAN LIN; DE GOOIJER, Mark C; ROIG, Eloy Moreno et al.Clinical cancer research (Print). 2014, Vol 20, Num 10, pp 2703-2713, issn 1078-0432, 11 p.Article

Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103)BEUMER, Jan H; OWZAR, Kouros; VIJ, Ravi et al.Cancer chemotherapy and pharmacology. 2014, Vol 74, Num 5, pp 927-938, issn 0344-5704, 12 p.Article

Sulforaphane Inhibits Prostate Carcinogenesis and Pulmonary Metastasis in TRAMP Mice in Association with Increased Cytotoxicity of Natural Killer CellsSINGH, Shivendra V; WARIN, Renaud; DESAI, Dhimant et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 5, pp 2117-2125, issn 0008-5472, 9 p.Article

Biomarkers of Phenethyl Isothiocyanate-Mediated Mammary Cancer Chemoprevention in a Clinically Relevant Mouse ModelSINGH, Shivendra V; KIM, Su-Hyeong; POWOLNY, Anna A et al.Journal of the National Cancer Institute. 2012, Vol 104, Num 16, pp 1228-1239, issn 0027-8874, 12 p.Article

In Vitro Circuit Stability of 5-Fluorouracil and Oxaliplatin in Support of Hyperthermic Isolated Hepatic PerfusionCOLVILLE, Heidi; DZADONY, Ryan; BEUMER, Jan H et al.The Journal of extra-corporeal technology. 2010, Vol 42, Num 1, pp 75-79, issn 0022-1058, 5 p.Article

Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776HOLLERAN, Julianne L; PARISE, Robert A; YELLOW-DUKE, Archibong E et al.Journal of pharmaceutical and biomedical analysis. 2010, Vol 52, Num 5, pp 714-720, issn 0731-7085, 7 p.Article

Effect of antacid on imatinib absorptionSPARANO, Brian A; EGORIN, Merrill J; PARISE, Robert A et al.Cancer chemotherapy and pharmacology. 2009, Vol 63, Num 3, pp 525-528, issn 0344-5704, 4 p.Article

Imatinib Mesylate Pharmacokinetics Before and After Sleeve Gastrectomy in a Morbidly Obese Patient with Chronic Myeloid LeukemiaPAVLOVSKY, Carolina; EGORIN, Merrill J; SHAH, Dhvani D et al.Pharmacotherapy. 2009, Vol 29, Num 9, pp 1152-1156, issn 0277-0008, 5 p.Article

Modulation of Gemcitabine (2',2'-Difluoro-2'-Deoxycytidine) Pharmacokinetics, Metabolism, and Bioavailability in Mice by 3,4,5,6-TetrahydrouridineBEUMER, Jan H; EISEMAN, Julie L; PARISE, Robert A et al.Clinical cancer research. 2008, Vol 14, Num 11, pp 3529-3535, issn 1078-0432, 7 p.Article

Calcium carbonate does not affect imatinib pharmacokinetics in healthy volunteersTAWBI, Hussein; CHRISTNER, Susan M; APPLEMAN, Leonard R et al.Cancer chemotherapy and pharmacology. 2014, Vol 73, Num 1, pp 207-211, issn 0344-5704, 5 p.Article

Calcium carbonate does not affect nilotinib pharmacokinetics in healthy volunteersTAWBI, Hussein A; TRAN, An L; BEUMER, Jan H et al.Cancer chemotherapy and pharmacology. 2013, Vol 72, Num 5, pp 1143-1147, issn 0344-5704, 5 p.Article

In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human cancer xenograftsJIANXIA GUO; CLAUSEN, Dana M; BEUMER, Jan H et al.Cancer chemotherapy and pharmacology. 2013, Vol 71, Num 2, pp 331-344, issn 0344-5704, 14 p.Article

A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and LymphomasKUMMAR, Shivaani; JIUPINGJI; NEWMAN, Edward M et al.Clinical cancer research (Print). 2012, Vol 18, Num 6, pp 1726-1734, issn 1078-0432, 9 p.Article

A local effect of CYP24 inhibition on lung tumor xenograft exposure to 1,25-dihydroxyvitamin D₃ is revealed using a novel LC-MS/MS assayBEUMER, Jan H; PARISE, Robert A; KANTEREWICZ, Beatriz et al.Steroids. 2012, Vol 77, Num 5, pp 477-483, issn 0039-128X, 7 p.Article

Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl⁺ hematological malignanciesBOSE, Prithviraj; PERKINS, Edward B; DOUGLAS FIGG, W et al.Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 6, pp 1657-1667, issn 0344-5704, 11 p.Article