Convenient synthesis of 5,6,11,12,17,18-hexahydrocyclononal[1,2-b :4,5-b' :7,8-b]tri-indole, a novel phytoestrogenSTAUB, Richard E; BJELDANES, Leonard F.Journal of organic chemistry. 2003, Vol 68, Num 1, pp 167-169, issn 0022-3263, 3 p.Article

Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-α expressionLEONG, Hoyee; FIRESTONE, Gary L; BJELDANES, Leonard F et al.Carcinogenesis (New York. Print). 2001, Vol 22, Num 11, pp 1809-1817, issn 0143-3334Article

DIM stimulates IFNy gene expression in human breast cancer cells via the specific activation of JNK and p38 pathwaysLING XUE; FIRESTONE, Gary L; BJELDANES, Leonard F et al.Oncogene (Basingstoke). 2005, Vol 24, Num 14, pp 2343-2353, issn 0950-9232, 11 p.Article

Inhibition of growth factor-induced Ras signaling in vascular endothelial cells and angiogenesis by 3,3'-diindolylmethaneXIAOFEI CHANG; FIRESTONE, Gary L; BJELDANES, Leonard F et al.Carcinogenesis (New York. Print). 2006, Vol 27, Num 3, pp 541-550, issn 0143-3334, 10 p.Article

Direct Inhibition of Elastase Activity by Indole-3-Carbinol Triggers a CD40-TRAF Regulatory Cascade That Disrupts NF-KB Transcriptional Activity in Human Breast Cancer CellsARONCHIK, Ida; BJELDANES, Leonard F; FIRESTONE, Gary L et al.Cancer research (Chicago, Ill.). 2010, Vol 70, Num 12, pp 4961-4971, issn 0008-5472, 11 p.Article

Bcl-2 family-mediated apoptotic effects of 3,3'-diindolylmethane (DIM) in human breast cancer cellsHONG, Chibo; FIRESTONE, Gary L; BJELDANES, Leonard F et al.Biochemical pharmacology. 2002, Vol 63, Num 6, pp 1085-1097, issn 0006-2952Article

3,3'-Diindolylmethane reduces levels of HIF-1α and HIF-1 activity in hypoxic cultured human cancer cellsRIBY, Jacques E; FIRESTONE, Gary L; BJELDANES, Leonard F et al.Biochemical pharmacology. 2008, Vol 75, Num 9, pp 1858-1867, issn 0006-2952, 10 p.Article

Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cellsZHANG, Joann; HSU, Jocelyn C; KINSETH, Matthew A et al.Cancer. 2003, Vol 98, Num 11, pp 2511-2520, issn 0008-543X, 10 p.Article

3,3'-diindolylmethane is a novel mitochondrial H⁺-ATP synthase inhibitor that can induce p21^Cip1/Waf1 expression by induction of oxidative stress in human breast cancer cellsYIXUAN GONG; SOHN, Heesook; LING XUE et al.Cancer research (Baltimore). 2006, Vol 66, Num 9, pp 4880-4887, issn 0008-5472, 8 p.Article

3,3'-Diindolylmethane induces a G₁ arrest in human prostate cancer cells irrespective of androgen receptor and p53 statusVIVAR, Omar I; LIN, Chia-Lei; FIRESTONE, Gary L et al.Biochemical pharmacology. 2009, Vol 78, Num 5, pp 469-476, issn 0006-2952, 8 p.Article

3,3'-Diindolylmethane stimulates murine immune function in vitro and in vivoLING XUE; PESTKA, James J; MAOXIANG LI et al.Journal of nutritional biochemistry. 2008, Vol 19, Num 5, pp 336-344, issn 0955-2863, 9 p.Article

3,3'-Diindolylmethane (DIM) induces a G₁ cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21^WAF1/CIP1 expressionCHIBO HONG; KIM, Hyeon-A; FIRESTONE, Gary L et al.Carcinogenesis (New York. Print). 2002, Vol 23, Num 8, pp 1297-1305, issn 0143-3334Article

Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactionsFIRESTONE, Gary L; BJELDANES, Leonard F.The Journal of nutrition. 2003, Vol 133, Num 7, pp 2448S-2455S, issn 0022-3166, SUPConference Paper

Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G₁ cell cycle arrest of human breast cancer cellsMARCONETT, Crystal N; SUNDAR, Shyam N; TSENG, Min et al.Carcinogenesis (New York. Print). 2011, Vol 32, Num 9, pp 1315-1323, issn 0143-3334, 9 p.Article

3,3'-Diindolylmethane inhibits angiogenesis and the growth of transplantable human breast carcinoma in athymic miceXIAOFEI CHANG; TOU, Janet C; CHIBO HONG et al.Carcinogenesis (New York. Print). 2005, Vol 26, Num 4, pp 771-778, issn 0143-3334, 8 p.Article

Pilot study: Effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancerDALESSANDRI, Kathie M; FIRESTONE, Gary L; FITCH, Mark D et al.Nutrition and cancer. 2004, Vol 50, Num 2, pp 161-167, issn 0163-5581, 7 p.Article

Indole-3-carbinol inhibition of androgen receptor expression and downregulation of androgen responsiveness in human prostate cancer cellsHSU, Jocelyn C; ZHANG, Joann; DEV, Anurupa et al.Carcinogenesis (New York. Print). 2005, Vol 26, Num 11, pp 1896-1904, issn 0143-3334, 9 p.Article

Indole-3-carbinol stimulates transcription of the interferon gamma receptor 1 gene and augments interferon responsiveness in human breast cancer cellsCHATTERJI, Urmi; RIBY, Jacques E; TANIGUCHI, Taketoshi et al.Carcinogenesis (New York. Print). 2004, Vol 25, Num 7, pp 1119-1128, issn 0143-3334, 10 p.Article

Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cellsBREW, Christine T; ARONCHIK, Ida; HSU, Jocelyn C et al.International journal of cancer. 2006, Vol 118, Num 4, pp 857-868, issn 0020-7136, 12 p.Article

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cellsJUMP, Sarah M; KUNG, Jenny; STAUB, Richard et al.Biochemical pharmacology. 2008, Vol 75, Num 3, pp 713-724, issn 0006-2952, 12 p.Article

Selective Activation of Estrogen Receptor-β Target Genes by 3,3'-DiindolylmethaneVIVAR, Omar I; SAUNIER, Elise F; LEITMAN, Dale C et al.Endocrinology (Philadelphia). 2010, Vol 151, Num 4, pp 1662-1667, issn 0013-7227, 6 p.Article

Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activityBREW, Christine T; ARONCHIK, Ida; KOSCO, Karena et al.International journal of cancer (Print). 2009, Vol 124, Num 10, pp 2294-2302, issn 0020-7136, 9 p.Article

Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor proteinHSU, Jocelyn C; DEV, Anurupa; WING, Aimee et al.Biochemical pharmacology. 2006, Vol 72, Num 12, pp 1714-1723, issn 0006-2952, 10 p.Article

Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic LeadsJOHNSON, Tyler A; SOHN, Johann; BRAY, Walter M et al.Journal of natural products (Print). 2011, Vol 74, Num 12, pp 2545-2555, issn 0163-3864, 11 p.Article

Myxobacteria versus sponge-derived alkaloids: The bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD librariesJOHNSON, Tyler A; SOHN, Johann; VASKE, Yvette M et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 14, pp 4348-4355, issn 0968-0896, 8 p.Article