Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure-safety relationship in patients with non-small cell lung cancerLU, Jian-Feng; EPPLER, Steve M; WOLF, Julie et al.Clinical pharmacology and therapeutics. 2006, Vol 80, Num 2, pp 136-145, issn 0009-9236, 10 p.Article

Modeling and simulation of sexual activity daily diary data of patients with female sexual arousal disorder treated with sildenafil citrate (Viagra®)CLARET, Laurent; COX, Eugene H; MCFADYEN, Lynn et al.Pharmaceutical research. 2006, Vol 23, Num 8, pp 1756-1764, issn 0724-8741, 9 p.Article

Pharmacokinetics/pharmacodynamics in drug development : An industrial perspectiveCHAIKIN, Philip; RHODES, Gerald R; BRUNO, Rene et al.Journal of clinical pharmacology. 2000, Vol 40, Num 12, pp 1428-1438, issn 0091-2700, 2Conference Paper

Clinical pharmacokinetics of bevacizumab in patients with solid tumorsLU, Jian-Feng; BRUNO, Rene; EPPLER, Steve et al.Cancer chemotherapy and pharmacology. 2008, Vol 62, Num 5, pp 779-786, issn 0344-5704, 8 p.Article

Population pharmacokinetics of trastuzumab in patients With HER2+ metastatic breast cancerBRUNO, Rene; WASHINGTON, Carla B; LU, Jian-Feng et al.Cancer chemotherapy and pharmacology. 2005, Vol 56, Num 4, pp 361-369, issn 0344-5704, 9 p.Article

Adaptation des quadratures de gauss-hermite pour améliorer l'estimation dans les modèles non linéaires à effets mixtes = Adaptation of Gauss-Hermite quadrature for the improvement of the estimation in nonlinear mixed modelsDIOT, Annabelle; MALLET, Alain; BRUNO, René et al.Journal de la Société française de statistique. 2002, Vol 143, Num 1-2, pp 195-204, issn 1625-7421, 10 p.Article

Fisher information matrix for non-linear mixed-effects models: evaluation and application for optimal design of enoxaparin population pharmacokineticsRETOUT, Sylvie; MENTRE, France; BRUNO, René et al.Statistics in medicine. 2002, Vol 21, Num 18, pp 2623-2639, issn 0277-6715, 17 p.Article

Development of a modeling framework to simulate efficacy endpoints for motesanib in patients with thyroid cancerCLARET, Laurent; LU, Jian-Feng; SUN, Yu-Nien et al.Cancer chemotherapy and pharmacology. 2010, Vol 66, Num 6, pp 1141-1149, issn 0344-5704, 9 p.Article

Clinical trial simulation of docetaxel in patients with cancer as a tool for dosage optimizationVEYRAT-FOLLET, Christine; BRUNO, René; OLIVARES, Robert et al.Clinical pharmacology and therapeutics. 2000, Vol 68, Num 6, pp 677-687, issn 0009-9236Article

Evaluation of Tumor-Size Response Metrics to Predict Overall Survival in Western and Chinese Patients With First-Line Metastatic Colorectal CancerCLARET, Laurent; GUPTA, Manish; HAN, Kelong et al.Journal of clinical oncology. 2013, Vol 31, Num 17, pp 2110-2114, issn 0732-183X, 5 p.Article

Population pharmacokinetics and pharmacokinetic-pharmacodynamic relationships for docetaxelBRUNO, René; VIVIER, Nicole; VEYRAT-FOLLET, Christine et al.Investigational new drugs. 2001, Vol 19, Num 2, pp 163-169, issn 0167-6997Article

α-1-Acid glycoprotein as an independent predictor for treatment effects and a prognostic factor of survival in patients with non-small cell lung cancer treated with docetaxelBRUNO, René; OLIVARES, Robert; BERILLE, Jocelyne et al.Clinical cancer research. 2003, Vol 9, Num 3, pp 1077-1082, issn 1078-0432, 6 p.Article

Population pharmacokinetic/pharmacodynamic modeling for the time course of tumor shrinkage by motesanib in thyroid cancer patientsLU, Jian-Feng; CLARET, Laurent; SUTJANDRA, Liviawati et al.Cancer chemotherapy and pharmacology. 2010, Vol 66, Num 6, pp 1151-1158, issn 0344-5704, 8 p.Article

Population pharmacokinetics and pharmacodynamics of enoxaparin in unstable angina and non-ST-segment elevation myocardial infarctionBRUNO, René; BAILLE, Pascale; RETOUT, Sylvie et al.British journal of clinical pharmacology. 2003, Vol 56, Num 4, pp 407-414, issn 0306-5251, 8 p.Article

Model-Based Prediction of Phase III Overall Survival in Colorectal Cancer on the Basis of Phase II Tumor DynamicsCLARET, Laurent; GIRARD, Pascal; HOFF, Paulo M et al.Journal of clinical oncology. 2009, Vol 27, Num 25, pp 4103-4108, issn 0732-183X, 6 p.Article

Phase I and pharmacokinetic study of docetaxel and irinotecan in patients with advanced solid tumorsCOUTEAU, Corinne; RISSE, Marie-Laure; ARMAND, Jean-Pierre et al.Journal of clinical oncology. 2000, Vol 18, Num 20, pp 3545-3552, issn 0732-183XArticle