Alzheimer drug design based on the amyloid hypothesisMUNOZ-TORRERO, Diego; CAMPS, Pelayo.Current pharmaceutical design. 2006, Vol 12, Num 33, issn 1381-6128, 129 p.Serial Issue

An Entry to Functionalized 2,8-Ethanonoradamantane DerivativesCAMPS, Pelayo; GOMEZ, Tania; MONASTEROLO, Claudio et al.Journal of organic chemistry. 2012, Vol 77, Num 24, pp 11270-11282, issn 0022-3263, 13 p.Article

Generation and reactions of two new functionalized tricyclo[3.3.0.0^3,7]oct-1(5)-ene derivativesCAMPS, Pelayo; MUNOZ, M. Rosa; VAZQUEZ, Santiago et al.Journal of organic chemistry. 2005, Vol 70, Num 5, pp 1945-1948, issn 0022-3263, 4 p.Article

Targeting beta-amyloid pathogenesis through acetylcholinesterase inhibitorsCASTRO, Ana; MARTINEZ, Ana.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4377-4387, issn 1381-6128, 11 p.Article

Molecular and biochemical features in Alzheimer's diseasePALLAS, Mercè; CAMINS, Antoni.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4389-4408, issn 1381-6128, 20 p.Article

Double Methylenecyclopentane Annulation of Succinimides: Easy Access to 3,7-Dioxobicyclo[3.3.0]octane-1,5-dicarboximidesCAMPS, Pelayo; FERNANDEZ, José A; RULL, Jordi et al.European journal of organic chemistry (Print). 2009, Num 18, pp 3081-3087, issn 1434-193X, 7 p.Article

Selective modulation of Aβ42 production in Alzheimer's disease : Non-steroidal anti-inflammatory drugs and beyondLEUCHTENBERGER, Stefanie; BEHER, Dirk; WEGGEN, Sascha et al.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4337-4355, issn 1381-6128, 19 p.Article

The development of preventives and therapeutics for Alzheimer's disease that inhibit the formation of β-amyloid fibrils (fAβ), as well as destabilize preformed fAβONO, Kenjiro; NAIKI, Hironobu; YAMADA, Masahito et al.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4357-4375, issn 1381-6128, 19 p.Article

Vaccine development for Alzheimer's diseaseDASILVA, Kevin A; AUBERT, Isabelle; MCLAURIN, Joanne et al.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4283-4293, issn 1381-6128, 11 p.Article

Views on amyloid hypothesis and secretase inhibitors for treating Alzheimer's disease : Progress and problemsNGUYEN, Jeffrey-Tri; YAMANI, Abdellah; KISO, Yoshiaki et al.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4295-4312, issn 1381-6128, 18 p.Article

Synthesis and pharmacological evaluation of huprine-tacrine heterodimers : Subnanomolar dual binding site acetylcholinesterase inhibitorsCAMPS, Pelayo; FORMOSA, Xavier; MUNOZ-TORRERO, Diego et al.Journal of medicinal chemistry (Print). 2005, Vol 48, Num 6, pp 1701-1704, issn 0022-2623, 4 p.Article

Pyrano[3,2-c]quinoline―6-Chlorotacrine Hybrids as a Novel Family of Acetylchotinesterase-and β-Amyloid-Directed Anti-Alzheimer CompoundsCAMPS, Pelayo; FORMOSA, Xavier; BARTOLINI, Manuela et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 17, pp 5365-5379, issn 0022-2623, 15 p.Article

Alternative syntheses of the new D_2d symmetric tetramethyl tricyclo-[3.3.0.0^3,7]octane-1,3,5,7-tetracarboxylateAYATS, Caries; CAMPS, Pelayo; DUQUE, Maria D et al.Journal of organic chemistry. 2003, Vol 68, Num 22, pp 8715-8718, issn 0022-3263, 4 p.Article

Gamma-secretase as a pharmacological target in Alzheimer disease research : When, why and how?ZIANI-CHERIF, Chewki; MOSTEFA-KARA, Bachir; BRIXI-GORMAT, Fatima Z et al.Current pharmaceutical design. 2006, Vol 12, Num 33, pp 4313-4335, issn 1381-6128, 23 p.Article

Characterisation of the anticholinesterase activity of two new tacrine-huperzine A hybridsDEL MAR ALCALA, Maria; VIVAS, Nuria Maria; HOSPITAL, Susana et al.Neuropharmacology. 2003, Vol 44, Num 6, pp 749-755, issn 0028-3908, 7 p.Article

Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitorsCAMPS, Pelayo; GOMEZ, Elena; MUNOZ-TORRERO, Diego et al.Journal of medicinal chemistry (Print). 2001, Vol 44, Num 26, pp 4733-4736, issn 0022-2623Article

New tacrine-huperzine A hybrids (huprines) : Highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's diseaseCAMPS, Pelayo; EL ACHAB, Rachid; MORRAL, Jordi et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 24, pp 4657-4666, issn 0022-2623Article

Novel Donepezil-Based Inhibitors of Acetyl-and Butyrylcholinesterase and Acetylcholinesterase-Induced β-Amyloid AggregationCAMPS, Pelayo; FORMOSA, Xavier; PALLAS, Mercè et al.Journal of medicinal chemistry (Print). 2008, Vol 51, Num 12, pp 3588-3598, issn 0022-2623, 11 p.Article

Neuroprotective effects of (±)-huprine Y on in vitro and in vivo models of excitoxicity damageCANUDAS, Anna M; PUBILL, David; SUREDA, Francesc X et al.Experimental neurology (Print). 2003, Vol 180, Num 2, pp 123-130, issn 0014-4886, 8 p.Article

The pharmacology of novel acetylcholinesterase inhibitors, (±)-huprines Y and X, on the Torpedo electric organROS, Esteve; ALEU, Jordi; GOMEZ DE ARANDA, Inmaculada et al.European journal of pharmacology. 2001, Vol 421, Num 2, pp 77-84, issn 0014-2999Article

Huprines as a new family of dual acting trypanocidal―antiplasmodial agentsDEFAUX, Julien; SALA, Marta; FORMOSA, Xavier et al.Bioorganic & medicinal chemistry. 2011, Vol 19, Num 5, pp 1702-1707, issn 0968-0896, 6 p.Article

New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activitiesDUQUE, Maria D; CAMPS, Pelayo; TORRES, Eva et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 1, pp 46-57, issn 0968-0896, 12 p.Article

Synthesis and pharmacological evaluation of several ring-contracted amantadine analogsCAMPS, Pelayo; DUQUE, Maria D; KELLY, John M et al.Bioorganic & medicinal chemistry. 2008, Vol 16, Num 23, pp 9925-9936, issn 0968-0896, 12 p.Article

Binding of 13-amidohuprines to acetylcholinesterase : Exploring the ligand-induced conformational change of the gly117-gly118 peptide bond in the oxyanion holeCAMPS, Pelayo; GOMEZ, Elena; MUNOZ-TORRERO, Diego et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 23, pp 6833-6840, issn 0022-2623, 8 p.Article

Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compoundsTORRES, Eva; DUQUE, María D; VANDERLINDEN, Evelien et al.Antiviral research. 2013, Vol 99, Num 3, pp 281-291, issn 0166-3542, 11 p.Article