Mechanism and stereochemistry of the germacradienol/germacrene D synthase of Streptomyces coelicolor A3(2)XIAOFEI HE; CANE, David E.Journal of the American Chemical Society. 2004, Vol 126, Num 9, pp 2678-2679, issn 0002-7863, 2 p.Article

Aristolochene synthase: Mechanistic analysis of active site residues by site-directed mutagenesisFELICETTI, Brunella; CANE, David E.Journal of the American Chemical Society. 2004, Vol 126, Num 23, pp 7212-7221, issn 0002-7863, 10 p.Article

Biosynthesis of vitamin B₆: direct identification of the product of the PdxA-catalyzed oxidation of 4-hydroxy-L-threonine-4-phosphate using electrospray ionization mass spectrometryBANKS, Jerel; CANE, David E.Bioorganic & medicinal chemistry letters (Print). 2004, Vol 14, Num 7, pp 1633-1636, issn 0960-894X, 4 p.Article

Genome mining in Streptomyces coelicolor : Molecular cloning and characterization of a new sesquiterpene synthaseXIN LIN; HOPSON, Russell; CANE, David E et al.Journal of the American Chemical Society. 2006, Vol 128, Num 18, pp 6022-6023, issn 0002-7863, 2 p.Article

Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosminJIAOYANG JIANG; XIAOFEI HE; CANE, David E et al.Journal of the American Chemical Society. 2006, Vol 128, Num 25, pp 8128-8129, issn 0002-7863, 2 p.Article

Modular polyketide synthases : Investigating intermodular communication using 6 deoxyerythronolide B synthase module 2MOFFET, David A; KHOSLA, Chaitan; CANE, David E et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 1, pp 213-216, issn 0960-894X, 4 p.Article

Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtIH, A non-heme iron dioxygenase of Streptomyces avermitilisZHENG YOU; OMURA, Satoshi; IKEDA, Haruo et al.Journal of the American Chemical Society. 2006, Vol 128, Num 20, pp 6566-6567, issn 0002-7863, 2 p.Article

Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthaseYIFENG YIN; HONGXIANG LU; KHOSLA, Chaitan et al.Journal of the American Chemical Society. 2003, Vol 125, Num 19, pp 5671-5676, issn 0002-7863, 6 p.Article

Precursor-directed polyketide biosynthesis in Escherichia coliKINOSHITA, Kenji; PFEIFER, Blaine A; KHOSLA, Chaitan et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 21, pp 3701-3704, issn 0960-894X, 4 p.Article

Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to ptii, a cytochrome p450 of Streptomyces avermitilisQUADERER, Richard; OMURA, Satoshi; IKEDA, Haruo et al.Journal of the American Chemical Society. 2006, Vol 128, Num 40, pp 13036-13037, issn 0002-7863, 2 p.Article

Molecular cloning, expression and characterization of the first three genes in the mevalonate-independent isoprenoid pathway in Streptomyces coelicolorCANE, David E; CHOW, Cathy; LILLO, Antonietta et al.Bioorganic & medicinal chemistry. 2001, Vol 9, Num 6, pp 1467-1477, issn 0968-0896Article

Cloning and characterization of Pfl_1841, a 2-methylenebornane synthase in Pseudomonas fluorescens PfO-1CHOU, Wayne K. W; IKEDA, Haruo; CANE, David E et al.Tetrahedron (Oxford. Print). 2011, Vol 67, Num 35, issn 0040-4020, 6410, 6627-6632 [7 p.]Article

Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin/methymycin polyketide synthaseWEIGUO HE; JIAQUAN WU; KHOSLA, Chaitan et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 2, pp 391-394, issn 0960-894X, 4 p.Article

Enhancing the modularity of the modular polyketide synthases: Transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylaseKUMAR, Pawan; KOPPISCH, Andrew T; CANE, David E et al.Journal of the American Chemical Society. 2003, Vol 125, Num 47, pp 14307-14312, issn 0002-7863, 6 p.Article

Erythromycin biosynthesis. The 4-pro-S Hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthaseYIFENG YIN; GOKHALE, Rajesh; KHOSLA, Chaitan et al.Bioorganic & medicinal chemistry letters (Print). 2001, Vol 11, Num 12, pp 1477-1479, issn 0960-894XArticle

Intermodular communication in Modular polyketide synthases: Structural and mutational analysis of linker mediated protein-protein recognitionKUMAR, Pawan; QING LI; CANE, David E et al.Journal of the American Chemical Society. 2003, Vol 125, Num 14, pp 4097-4102, issn 0002-7863, 6 p.Article

Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/ methymycin polyketide synthaseJIAQUAN WU; ZALESKI, Toby J; VALENZANO, Chiara et al.Journal of the American Chemical Society. 2005, Vol 127, Num 49, pp 17393-17404, issn 0002-7863, 12 p.Article

Biosynthesis of complex polyketides in a metabolically engineered strain of E. coliPFEIFER, Blaine A; ADMIRAAL, Suzanne J; GRAMAJO, Hugo et al.Science (Washington, D.C.). 2001, Vol 291, Num 5509, pp 1790-1792, issn 0036-8075Article

Pentalenene synthase. Analysis of active site residues by site-directed mutagenesisSEEMANN, Myriam; GUANGZHI ZHAI; DE KRAKER, Jan-Willem et al.Journal of the American Chemical Society. 2002, Vol 124, Num 26, pp 7681-7689, issn 0002-7863Article

Isolation and Characterization of the Gene Associated with Geosmin Production in CyanobacteriaGIGLIO, Steven; JIAOYANG JIANG; SAINT, Christopher P et al.Environmental science & technology. 2008, Vol 42, Num 21, pp 8027-8032, issn 0013-936X, 6 p.Article

Functional expression and characterization of erya, the erythritol kinase of Brucella abortus, and enzymatic synthesis of L-erythritol-4-phosphateLILLO, Antonietta M; TETZLAFF, Charles N; SANGARI, Félix J et al.Bioorganic & medicinal chemistry letters (Print). 2003, Vol 13, Num 4, pp 737-739, issn 0960-894X, 3 p.Article

Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modulesHANS, Marcus; HORNUNG, Andreas; DZIARNOWSKI, Agnieszka et al.Journal of the American Chemical Society. 2003, Vol 125, Num 18, pp 5366-5374, issn 0002-7863, 9 p.Article

Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthaseKAPUR, Shiven; WORTHINGTON, Andrew; YINYAN TANG et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 10, pp 3034-3038, issn 0960-894X, 5 p.Article

Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineeringLOMBO, Felipe; PFEIFER, Blaine; LEAF, Timothy et al.Biotechnology progress. 2001, Vol 17, Num 4, pp 612-617, issn 8756-7938Article

Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthaseCHEN, Alice Y; SCHNARR, Nathan A; KIM, Chu-Young et al.Journal of the American Chemical Society. 2006, Vol 128, Num 9, pp 3067-3074, issn 0002-7863, 8 p.Article