Receptor tyrosine kinases as targets for anticancer therapeuticsCARLOMAGNO, Francesca; SANTORO, Massimo.Current medicinal chemistry. 2005, Vol 12, Num 15, pp 1773-1781, issn 0929-8673, 9 p.Article

RET Is a Heat Shock Protein 90 (HSP90) Client Protein and Is Knocked Down upon HSP90 Pharmacological BlockALFANO, Luigi; GUIDA, Teresa; PROVITERA, Livia et al.The Journal of clinical endocrinology and metabolism. 2010, Vol 95, Num 7, pp 3552-3557, issn 0021-972X, 6 p.Article

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteinsIERVOLINO, Angela; IULIANO, Rodolfo; TRAPASSO, Francesco et al.Cancer research (Baltimore). 2006, Vol 66, Num 12, pp 6280-6287, issn 0008-5472, 8 p.Article

Identification of Polo-like Kinase 1 as a Potential Therapeutic Target in Anaplastic Thyroid CarcinomaCLAUDIO NAPPI, Tito; SALERNO, Paolo; ZITZELSBERGER, Horst et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 5, pp 1916-1923, issn 0008-5472, 8 p.Article

The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenesCARLOMAGNO, Francesca; VITAGLIANO, Donata; GUIDA, Teresa et al.Cancer research (Baltimore). 2002, Vol 62, Num 4, pp 1077-1082, issn 0008-5472Article

Minireview: RET: Normal and abnormal functionsSANTORO, Massimo; MELILLO, Rosa Marina; CARLOMAGNO, Francesca et al.Endocrinology (Philadelphia). 2004, Vol 145, Num 12, pp 5448-5451, issn 0013-7227, 4 p.Article

Sorafenib inhibits imatinib-resistant KIT and platelet-derived growth factor receptor β gatekeeper mutantsGUIDA, Teresa; ANAGANTI, Suresh; PROVITERA, Livia et al.Clinical cancer research. 2007, Vol 13, Num 11, pp 3363-3369, issn 1078-0432, 7 p.Article

Protein kinase Cα activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinaseANDREOZZI, Francesco; MELILLO, Rosa Marina; FORMISANO, Pietro et al.Oncogene (Basingstoke). 2003, Vol 22, Num 19, pp 2942-2949, issn 0950-9232, 8 p.Article

Constitutive and AP20187-induced ret activation in photoreceptors does not protect from light-induced damageALLOCCA, Mariacarmela; DI VICINO, Umberto; PETRILLO, Marco et al.Investigative ophthalmology & visual science. 2007, Vol 48, Num 11, pp 5199-5206, issn 0146-0404, 8 p.Article

BRAF is a therapeutic target in aggressive thyroid carcinomaSALVATORE, Giuliana; DE FALCO, Valentina; SALERNO, Paolo et al.Clinical cancer research. 2006, Vol 12, Num 5, pp 1623-1629, issn 1078-0432, 7 p.Article

Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomasCASTELLONE, Maria D; GUARINO, Valentina; FUSCO, Alfredo et al.Oncogene (Basingstoke). 2004, Vol 23, Num 35, pp 5958-5967, issn 0950-9232, 10 p.Article

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2)CARLOMAGNO, Francesca; VITAGLIANO, Donata; GUIDA, Teresa et al.The Journal of clinical endocrinology and metabolism. 2003, Vol 88, Num 4, pp 1897-1902, issn 0021-972X, 6 p.Article

In vivo and in vitro characterization of a novel germline RET mutation associated with low-penetrant nonaggressive familial medullary thyroid carcinomaD'ALOISO, Leonardo; CARLOMAGNO, Francesca; FILETTI, Sebastiano et al.The Journal of clinical endocrinology and metabolism. 2006, Vol 91, Num 3, pp 754-759, issn 0021-972X, 6 p.Article

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cellsVITAGLIANO, Donata; CARLOMAGNO, Francesca; SANTORO, Massimo et al.Cancer research (Baltimore). 2004, Vol 64, Num 11, pp 3823-3829, issn 0008-5472, 7 p.Article

The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinomaMELILLO, Rosa Marina; CIRAFICI, Anna Maria; SANTORO, Massimo et al.The American journal of pathology. 2004, Vol 165, Num 2, pp 511-521, issn 0002-9440, 11 p.Article

Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinomaBASOLO, Fulvio; GIANNINI, Riccardo; MICCOLI, Paolo et al.The American journal of pathology. 2002, Vol 160, Num 1, pp 247-254, issn 0002-9440Article

BAY 43-9006 inhibition of oncogenic RET mutantsCARLOMAGNO, Francesca; ANAGANTI, Suresh; GUIDA, Teresa et al.Journal of the National Cancer Institute. 2006, Vol 98, Num 5, pp 326-334, issn 0027-8874, 9 p.Article

Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinomaGUIDA, Teresa; SALVATORE, Giuliana; FAVIANA, Pinuccia et al.The Journal of clinical endocrinology and metabolism. 2005, Vol 90, Num 8, pp 4703-4709, issn 0021-972X, 7 p.Article

Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitorsCARLOMAGNO, Francesca; GUIDA, Teresa; ANAGANTI, Suresh et al.Oncogene (Basingstoke). 2004, Vol 23, Num 36, pp 6056-6063, issn 0950-9232, 8 p.Article

Antitumor effects of ZD6474, a small molecule Vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinaseCIARDIELLO, Fortunato; CAPUTO, Rosa; TORTORA, Giampaolo et al.Clinical cancer research. 2003, Vol 9, Num 4, pp 1546-1556, issn 1078-0432, 11 p.Article

Cloning and molecular characterization of a novel gene strongly induced by the adenovirus E1A gene in rat thyroid cellsVISCONTI, Roberta; SCHEPIS, Filippo; FUSCO, Alfredo et al.Oncogene (Basingstoke). 2003, Vol 22, Num 7, pp 1087-1097, issn 0950-9232, 11 p.Article

ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinasesCARLOMAGNO, Francesca; VITAGLIANO, Donata; GUIDA, Teresa et al.Cancer research (Baltimore). 2002, Vol 62, Num 24, pp 7284-7290, issn 0008-5472, 7 p.Article

The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret : Evidence for a competition between Shc and IRS-1 for the binding to RetMELILLO, Rosa Marina; CARLOMAGNO, Francesca; DE VITA, Gabriella et al.Oncogene (Basingstoke). 2001, Vol 20, Num 2, pp 209-218, issn 0950-9232Article

The extent of linkage disequilibrium in four populations with distinct demographic historiesDUNNING, Alison M; DUROCHER, Francine; LAI, Eric et al.American journal of human genetics. 2000, Vol 67, Num 6, pp 1544-1554, issn 0002-9297Article