Influence of single nucleotide polymorphisms on thrombin generation in factor V Leiden heterozygotesSEGERS, Olivier; SIMIONI, Paolo; TORMENE, Daniela et al.Thrombosis and haemostasis. 2014, Vol 111, Num 3, pp 438-446, issn 0340-6245, 9 p.Article

Advances in understanding the bleeding diathesis in factor V deficiencyDUCKERS, Connie; SIMIONI, Paolo; JAN ROSING et al.British journal of haematology. 2009, Vol 146, Num 1, pp 17-26, issn 0007-1048, 10 p.Article

Factor V Leiden: a disorder of factor V anticoagulant functionCASTOLDI, Elisabetta; ROSING, Jan.Current opinion in hematology. 2004, Vol 11, Num 3, pp 176-181, issn 1065-6251, 6 p.Article

Protein S levels modulate the activated protein C resistance phenotype induced by elevated prothrombin levelsBRUGGE, Jeroen M; TANS, Guido; ROSING, Jan et al.Thrombosis and haemostasis. 2006, Vol 95, Num 2, pp 236-242, issn 0340-6245, 7 p.Article

A missense mutation (Y1702C) in the coagulation factor V gene is a frequent cause of factor V deficiency in the Italian populationCASTOLDI, Elisabetta; LUNGHI, Barbara; MINGOZZI, Federico et al.Haematologica (Roma). 2001, Vol 86, Num 6, pp 629-633, issn 0390-6078Article

Thrombin generation as an intermediate phenotype for venous thrombosis: A proof-of-concept studySEGERS, Olivier; VAN OERLE, René; TEN CATE, Hugo et al.Thrombosis and haemostasis. 2010, Vol 103, Num 1, pp 114-122, issn 0340-6245, 9 p.Article

Functional properties of factor V and factor Va encoded by the R2-geneHOEKEMA, Lico; CASTOLDI, Elisabetta; TANS, Guido et al.Thrombosis and haemostasis. 2001, Vol 85, Num 1, pp 75-81, issn 0340-6245Article

A highly polymorphic microsatellite in the factor V gene is an informative tool for the study of factor V-related disordersCASTOLDI, Elisabetta; LUNGHI, Barbara; MINGOZZI, Federico et al.British journal of haematology. 2001, Vol 114, Num 4, pp 868-870, issn 0007-1048Article

Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiencyDUCKERS, Connie; SIMIONI, Paolo; SPIEZIA, Luca et al.Blood. 2008, Vol 112, Num 9, pp 3615-3623, issn 0006-4971, 9 p.Article

Regulation of coagulation by protein SCASTOLDI, Elisabetta; HACKENG, Tilman M.Current opinion in hematology. 2008, Vol 15, Num 5, pp 529-536, issn 1065-6251, 8 p.Article

An underestimated combination of opposites resulting in enhanced thrombotic tendencySIMIONI, Paolo; CASTOLDI, Elisabetta; LUNGHI, Barbara et al.Blood. 2005, Vol 106, Num 7, pp 2363-2365, issn 0006-4971, 3 p.Article

Thrombin generation and activated protein C resistance in patients with essential thrombocythemia and polycythemia veraMARCHETTI, Marina; CASTOLDI, Elisabetta; SPRONK, Henri M. H et al.Blood. 2008, Vol 112, Num 10, pp 4061-4068, issn 0006-4971, 8 p.Article

Endogenous factor V synthesis in megakaryocytes contributes negligibly to the platelet factor V poolTHOMASSEN, M. Christella L. G. D; CASTOLDI, Elisabetta; TANS, Guido et al.Haematologica (Roma). 2003, Vol 88, Num 10, pp 1150-1156, issn 0390-6078, 7 p.Article

Similar hypercoagulable state and thrombosis risk in type I and type III protein S-deficient individuals from families with mixed type I/III protein S deficiencyCASTOLDI, Elisabetta; MAURISSEN, Lisbeth F. A; TORMENE, Daniela et al.Haematologica (Roma). 2010, Vol 95, Num 9, pp 1563-1571, issn 0390-6078, 9 p.Article

A FV multiallelic marker detects genetic components of APC resistance contributing to venous thromboembolism in FV Leiden carriersMINGOZZI, Federico; LEGNANI, Cristina; LUNGHI, Barbara et al.Thrombosis and haemostasis. 2003, Vol 89, Num 6, pp 983-989, issn 0340-6245, 7 p.Article

Reduced factor V concentration and altered FV₁/FV₂ ratio do not fully explain R2-associated APC-resistanceGOVERS-RIEMSLAG, Jose W. P; CASTOLDI, Elisabetta; NICOLAES, Gerry A. F et al.Thrombosis and haemostasis. 2002, Vol 88, Num 3, pp 444-449, issn 0340-6245, 6 p.Article

Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptomsDUCKERS, Connie; SIMIONI, Paolo; SPIEZIA, Luca et al.Blood. 2010, Vol 115, Num 4, pp 879-886, issn 0006-4971, 8 p.Article

Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutationsCASTOLDI, Elisabetta; BRUGGE, Jeroen M; NICOLAES, Gerry A. F et al.Blood. 2004, Vol 103, Num 11, pp 4173-4179, issn 0006-4971, 7 p.Article

Coinheritance of factor V (FV) Leiden enhances thrombin formation and is associated with a mild bleeding phenotype in patients homozygous for the FVII 9726+5G>A (FVII Lazio) mutationCASTOLDI, Elisabetta; GOVERS-RIEMSLAG, Josh W. P; PINOTTI, Mirko et al.Blood. 2003, Vol 102, Num 12, pp 4014-4020, issn 0006-4971, 7 p.Article